Octominin Inhibits LPS-Induced Chemokine and Pro-inflammatory Cytokine Secretion from RAW 264.7 Macrophages via Blocking TLRs/NF-κB Signal Transduction

Octominin Inhibits LPS-Induced Chemokine and Pro-inflammatory Cytokine Secretion from RAW 264.7 Macrophages via Blocking TLRs/NF-κB Signal Transduction

Inflammation is a well-organized innate immune response that plays an important role during the pathogen attacks and mechanical injuries. The Toll-like receptors (TLR)/nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a major signal transduction pathway observed in RAW 264.7...

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Bibliographic Details
Main Authors: K. K. Asanka Sanjeewa, D. P. Nagahawatta, Hye-Won Yang, Jae Young Oh, Thilina U. Jayawardena, You-Jin Jeon, Mahanama De Zoysa, Ilson Whang, Bomi Ryu
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Biomolecules
Subjects:
<i>Octopus minor</i>
peptide
inflammation
chemokines
RAW 264.7
NF-κB
Online Access:https://www.mdpi.com/2218-273X/10/4/511

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