| Summary: | The main treatment in nearly every case of thyroid cancer is surgery. The exception often refers to anaplastic carcinoma because this cancer is already widespread at the time of diagnosis. Most of the cases are treated with thyroidectomy, but small tumors that spread inside the thyroid gland might be treated by lobectomy. Intrathoracic goiter accounts for 5.8% of all mediastinal masses. On the other hand, the incidence of thyroid malignancy in cervico-mediastinal thyroid masses is 7,7%. In such cases, total thyroidectomy with en block removal of the mediastinal portion of the gland is the treatment of choice. We present a case of a 34-year-old woman with cervico-mediastinal malignant goiter.
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