Polymer-Based Hybrid Nanoarchitectures for Cancer Therapy Applications
Globally, cancer is affecting societies and is becoming an important cause of death. Chemotherapy can be highly effective, but it is associated with certain problems, such as undesired targeting and multidrug resistance. The other advanced therapies, such as gene therapy and peptide therapy, do not...
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-07-01
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| Series: | Polymers |
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| Online Access: | https://www.mdpi.com/2073-4360/14/15/3027 |
| _version_ | 1797440976999940096 |
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| author | Arun Kumar Mirkomil Sharipov Abbaskhan Turaev Shavkatjon Azizov Ismatdjan Azizov Edwin Makhado Abbas Rahdar Deepak Kumar Sadanand Pandey |
| author_facet | Arun Kumar Mirkomil Sharipov Abbaskhan Turaev Shavkatjon Azizov Ismatdjan Azizov Edwin Makhado Abbas Rahdar Deepak Kumar Sadanand Pandey |
| author_sort | Arun Kumar |
| collection | DOAJ |
| description | Globally, cancer is affecting societies and is becoming an important cause of death. Chemotherapy can be highly effective, but it is associated with certain problems, such as undesired targeting and multidrug resistance. The other advanced therapies, such as gene therapy and peptide therapy, do not prove to be effective without a proper delivery medium. Polymer-based hybrid nanoarchitectures have enormous potential in drug delivery. The polymers used in these nanohybrids (NHs) provide them with their distinct properties and also enable the controlled release of the drugs. This review features the recent use of polymers in the preparation of different nanohybrids for cancer therapy published since 2015 in some reputed journals. The polymeric nanohybrids provide an advantage in drug delivery with the controlled and targeted delivery of a payload and the irradiation of cancer by chemotherapeutical and photodynamic therapy. |
| first_indexed | 2024-03-09T12:16:14Z |
| format | Article |
| id | doaj.art-ceeda240946540d69eb034f8d22c7cc3 |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-03-09T12:16:14Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-ceeda240946540d69eb034f8d22c7cc32023-11-30T22:46:22ZengMDPI AGPolymers2073-43602022-07-011415302710.3390/polym14153027Polymer-Based Hybrid Nanoarchitectures for Cancer Therapy ApplicationsArun Kumar0Mirkomil Sharipov1Abbaskhan Turaev2Shavkatjon Azizov3Ismatdjan Azizov4Edwin Makhado5Abbas Rahdar6Deepak Kumar7Sadanand Pandey8Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan 173229, IndiaDepartment of Chemistry, Changwon National University, Changwon 51140, KoreaLaboratory of Biological Active Macromolecular Systems, Institute of Bioorganic Chemistry, Uzbekistan Academy of Sciences, Tashkent 100125, UzbekistanLaboratory of Biological Active Macromolecular Systems, Institute of Bioorganic Chemistry, Uzbekistan Academy of Sciences, Tashkent 100125, UzbekistanState Center for Expertise and Standardization of Medicines, Medical Devices, and Medical Equipment, State Unitary Enterprise, Tashkent 100002, UzbekistanDepartment of Chemistry, School of Physical and Mineral Sciences, University of Limpopo, Polokwane 0727, South AfricaDepartment of Physics, Faculty of Science, University of Zabol, Zabol 538-98615, IranDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan 173229, IndiaDepartment of Chemistry, College of Natural Sciences, Yeungnam University, 280 Daehak-Ro, Gyeongsan 38541, KoreaGlobally, cancer is affecting societies and is becoming an important cause of death. Chemotherapy can be highly effective, but it is associated with certain problems, such as undesired targeting and multidrug resistance. The other advanced therapies, such as gene therapy and peptide therapy, do not prove to be effective without a proper delivery medium. Polymer-based hybrid nanoarchitectures have enormous potential in drug delivery. The polymers used in these nanohybrids (NHs) provide them with their distinct properties and also enable the controlled release of the drugs. This review features the recent use of polymers in the preparation of different nanohybrids for cancer therapy published since 2015 in some reputed journals. The polymeric nanohybrids provide an advantage in drug delivery with the controlled and targeted delivery of a payload and the irradiation of cancer by chemotherapeutical and photodynamic therapy.https://www.mdpi.com/2073-4360/14/15/3027polymeric nanohybridscancer therapychitosan-based nanohybridsdrug deliverypH-based targeting |
| spellingShingle | Arun Kumar Mirkomil Sharipov Abbaskhan Turaev Shavkatjon Azizov Ismatdjan Azizov Edwin Makhado Abbas Rahdar Deepak Kumar Sadanand Pandey Polymer-Based Hybrid Nanoarchitectures for Cancer Therapy Applications Polymers polymeric nanohybrids cancer therapy chitosan-based nanohybrids drug delivery pH-based targeting |
| title | Polymer-Based Hybrid Nanoarchitectures for Cancer Therapy Applications |
| title_full | Polymer-Based Hybrid Nanoarchitectures for Cancer Therapy Applications |
| title_fullStr | Polymer-Based Hybrid Nanoarchitectures for Cancer Therapy Applications |
| title_full_unstemmed | Polymer-Based Hybrid Nanoarchitectures for Cancer Therapy Applications |
| title_short | Polymer-Based Hybrid Nanoarchitectures for Cancer Therapy Applications |
| title_sort | polymer based hybrid nanoarchitectures for cancer therapy applications |
| topic | polymeric nanohybrids cancer therapy chitosan-based nanohybrids drug delivery pH-based targeting |
| url | https://www.mdpi.com/2073-4360/14/15/3027 |
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