Convergence of 3D Bioprinting and Nanotechnology in Tissue Engineering Scaffolds
Three-dimensional (3D) bioprinting has emerged as a promising scaffold fabrication strategy for tissue engineering with excellent control over scaffold geometry and microstructure. Nanobiomaterials as bioinks play a key role in manipulating the cellular microenvironment to alter its growth and devel...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Biomimetics |
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| Online Access: | https://www.mdpi.com/2313-7673/8/1/94 |
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| author | Shike Zhang Xin Chen Mengyao Shan Zijuan Hao Xiaoyang Zhang Lingxian Meng Zhen Zhai Linlin Zhang Xuying Liu Xianghong Wang |
| author_facet | Shike Zhang Xin Chen Mengyao Shan Zijuan Hao Xiaoyang Zhang Lingxian Meng Zhen Zhai Linlin Zhang Xuying Liu Xianghong Wang |
| author_sort | Shike Zhang |
| collection | DOAJ |
| description | Three-dimensional (3D) bioprinting has emerged as a promising scaffold fabrication strategy for tissue engineering with excellent control over scaffold geometry and microstructure. Nanobiomaterials as bioinks play a key role in manipulating the cellular microenvironment to alter its growth and development. This review first introduces the commonly used nanomaterials in tissue engineering scaffolds, including natural polymers, synthetic polymers, and polymer derivatives, and reveals the improvement of nanomaterials on scaffold performance. Second, the 3D bioprinting technologies of inkjet-based bioprinting, extrusion-based bioprinting, laser-assisted bioprinting, and stereolithography bioprinting are comprehensively itemized, and the advantages and underlying mechanisms are revealed. Then the convergence of 3D bioprinting and nanotechnology applications in tissue engineering scaffolds, such as bone, nerve, blood vessel, tendon, and internal organs, are discussed. Finally, the challenges and perspectives of convergence of 3D bioprinting and nanotechnology are proposed. This review will provide scientific guidance to develop 3D bioprinting tissue engineering scaffolds by nanotechnology. |
| first_indexed | 2024-03-11T06:52:58Z |
| format | Article |
| id | doaj.art-cef11b5d47b9491ca5055a229a7cfd50 |
| institution | Directory Open Access Journal |
| issn | 2313-7673 |
| language | English |
| last_indexed | 2024-03-11T06:52:58Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomimetics |
| spelling | doaj.art-cef11b5d47b9491ca5055a229a7cfd502023-11-17T09:50:13ZengMDPI AGBiomimetics2313-76732023-02-01819410.3390/biomimetics8010094Convergence of 3D Bioprinting and Nanotechnology in Tissue Engineering ScaffoldsShike Zhang0Xin Chen1Mengyao Shan2Zijuan Hao3Xiaoyang Zhang4Lingxian Meng5Zhen Zhai6Linlin Zhang7Xuying Liu8Xianghong Wang9Henan Innovation Center for Functional Polymer Membrane Materials, Henan Key Laboratory of Advanced Nylon Materials and Application, School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001, ChinaNational Engineering Research Center of Wheat and Corn Further Processing, College of Food Science and Engineering, Henan University of Technology, Zhengzhou 450001, ChinaHenan Innovation Center for Functional Polymer Membrane Materials, Henan Key Laboratory of Advanced Nylon Materials and Application, School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001, ChinaHenan Innovation Center for Functional Polymer Membrane Materials, Xinxiang 453000, ChinaHenan Innovation Center for Functional Polymer Membrane Materials, Henan Key Laboratory of Advanced Nylon Materials and Application, School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001, ChinaHenan Innovation Center for Functional Polymer Membrane Materials, Henan Key Laboratory of Advanced Nylon Materials and Application, School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001, ChinaHenan Innovation Center for Functional Polymer Membrane Materials, Henan Key Laboratory of Advanced Nylon Materials and Application, School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001, ChinaHenan Innovation Center for Functional Polymer Membrane Materials, Henan Key Laboratory of Advanced Nylon Materials and Application, School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001, ChinaHenan Innovation Center for Functional Polymer Membrane Materials, Henan Key Laboratory of Advanced Nylon Materials and Application, School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001, ChinaHenan Innovation Center for Functional Polymer Membrane Materials, Henan Key Laboratory of Advanced Nylon Materials and Application, School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001, ChinaThree-dimensional (3D) bioprinting has emerged as a promising scaffold fabrication strategy for tissue engineering with excellent control over scaffold geometry and microstructure. Nanobiomaterials as bioinks play a key role in manipulating the cellular microenvironment to alter its growth and development. This review first introduces the commonly used nanomaterials in tissue engineering scaffolds, including natural polymers, synthetic polymers, and polymer derivatives, and reveals the improvement of nanomaterials on scaffold performance. Second, the 3D bioprinting technologies of inkjet-based bioprinting, extrusion-based bioprinting, laser-assisted bioprinting, and stereolithography bioprinting are comprehensively itemized, and the advantages and underlying mechanisms are revealed. Then the convergence of 3D bioprinting and nanotechnology applications in tissue engineering scaffolds, such as bone, nerve, blood vessel, tendon, and internal organs, are discussed. Finally, the challenges and perspectives of convergence of 3D bioprinting and nanotechnology are proposed. This review will provide scientific guidance to develop 3D bioprinting tissue engineering scaffolds by nanotechnology.https://www.mdpi.com/2313-7673/8/1/943D bioprintingnanobiomaterialsnanotechnologytissue engineering scaffolds |
| spellingShingle | Shike Zhang Xin Chen Mengyao Shan Zijuan Hao Xiaoyang Zhang Lingxian Meng Zhen Zhai Linlin Zhang Xuying Liu Xianghong Wang Convergence of 3D Bioprinting and Nanotechnology in Tissue Engineering Scaffolds Biomimetics 3D bioprinting nanobiomaterials nanotechnology tissue engineering scaffolds |
| title | Convergence of 3D Bioprinting and Nanotechnology in Tissue Engineering Scaffolds |
| title_full | Convergence of 3D Bioprinting and Nanotechnology in Tissue Engineering Scaffolds |
| title_fullStr | Convergence of 3D Bioprinting and Nanotechnology in Tissue Engineering Scaffolds |
| title_full_unstemmed | Convergence of 3D Bioprinting and Nanotechnology in Tissue Engineering Scaffolds |
| title_short | Convergence of 3D Bioprinting and Nanotechnology in Tissue Engineering Scaffolds |
| title_sort | convergence of 3d bioprinting and nanotechnology in tissue engineering scaffolds |
| topic | 3D bioprinting nanobiomaterials nanotechnology tissue engineering scaffolds |
| url | https://www.mdpi.com/2313-7673/8/1/94 |
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