Detection of microbial translocation in HIV and SIV infection using the Limulus amebocyte lysate assay is masked by serum and plasma.

Detection of microbial translocation in HIV and SIV infection using the Limulus amebocyte lysate assay is masked by serum and plasma.

Microbial translocation (MT) is thought to be a major contributor to the pathogenesis of HIV-related immune activation, and circulating lipopolysaccharide (LPS) from gram-negative bacteria is the principle measurement of this process. However, related research has been impeded by inconsistent LPS te...

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Bibliographic Details
Main Authors: Ashwin Balagopal, Lucio Gama, Veronica Franco, Julia N Russell, Jeffrey Quinn, Yvonne Higgins, Laura M Smeaton, Janice E Clements, David L Thomas, Amita Gupta, NWCS 319 and ACTG 5175 study team
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3409852?pdf=render

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