Identification of novel early pancreatic cancer biomarkers KIF5B and SFRP2 from “first contact” interactions in the tumor microenvironment

Identification of novel early pancreatic cancer biomarkers KIF5B and SFRP2 from “first contact” interactions in the tumor microenvironment

Abstract Background Pancreatic cancer is one of the most difficult cancers to detect early and most patients die from complications arising due to distant organ metastases. The lack of bona fide early biomarkers is one of the primary reasons for late diagnosis of pancreatic cancer. It is a multifact...

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Bibliographic Details
Main Authors: Harrys Kishore Charles Jacob, Rossana Signorelli, John Lalith Charles Richard, Tyler Kashuv, Shweta Lavania, Ashley Middleton, Beatriz Aguilar Gomez, Anthony Ferrantella, Haleh Amirian, Junyi Tao, Ayse Burcu Ergonul, Melinda Minucci Boone, Marco Hadisurya, Weiguo Andy Tao, Anton Iliuk, Manoj Kumar Kashyap, Monica Garcia-Buitrago, Rajinder Dawra, Ashok Kumar Saluja
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Pancreatic Cancer
Extracellular Vesicles
EVtrap
Proteomics
Tumor-Microenvironment
SFRP2
Online Access:https://doi.org/10.1186/s13046-022-02425-y

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