Toxoplasma gondii inhibits the expression of autophagy-related genes through AKT-dependent inactivation of the transcription factor FOXO3a
ABSTRACT The intracellular parasite Toxoplasma gondii induces host AKT activation to prevent autophagy-mediated clearance; however, the molecular underpinnings are not fully understood. Autophagy can be negatively regulated through AKT-sensitive phosphorylation and nuclear export of the transcriptio...
Main Authors: | Andres Felipe Diez, Louis-Philippe Leroux, Sophie Chagneau, Alexandra Plouffe, Mackenzie Gold, Visnu Chaparro, Maritza Jaramillo |
---|---|
Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2023-08-01
|
Series: | mBio |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/mbio.00795-23 |
Similar Items
-
A Window to Toxoplasma gondii Egress
by: Lucio Ayres Caldas, et al.
Published: (2018-08-01) -
Mucosal immunity in Toxoplasma gondii infection
by: Schulthess J., et al.
Published: (2008-09-01) -
Toxoplasma gondii, “new” genotypes and virulence
by: Dardé M.L.
Published: (2008-09-01) -
Veterinary vaccines against Toxoplasma gondii
by: Elisabeth A Innes, et al.
Published: (2009-03-01) -
Halk Sağlığı bakışıyla Toxoplasma gondii/Toxoplasma gondii With Public Health’s Perspective
by: Sibel Cevizci, et al.
Published: (2013-04-01)