Primary Extra-Pleura Leiomyoma: A Case Report and Literature Review

Leiomyomas are a common type of benign soft tissue tumor arising from smooth muscle, most often occurring within females’ genitourinary and gastrointestinal tract. However, primary leiomyomas of the chest wall residing in the extra-pleural space are an extremely rare subset of leiomyomatous lesion p...

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Main Authors: Asad Ullah, G. Taylor Patterson, Intisar Ghleilib, Islam A. Elhelf, Nikhil G. Patel, Nagla A. Karim
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Current Oncology
Subjects:
Online Access:https://www.mdpi.com/1718-7729/29/5/240
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author Asad Ullah
G. Taylor Patterson
Intisar Ghleilib
Islam A. Elhelf
Nikhil G. Patel
Nagla A. Karim
author_facet Asad Ullah
G. Taylor Patterson
Intisar Ghleilib
Islam A. Elhelf
Nikhil G. Patel
Nagla A. Karim
author_sort Asad Ullah
collection DOAJ
description Leiomyomas are a common type of benign soft tissue tumor arising from smooth muscle, most often occurring within females’ genitourinary and gastrointestinal tract. However, primary leiomyomas of the chest wall residing in the extra-pleural space are an extremely rare subset of leiomyomatous lesion presentation. We present a case of a fifty-two-year-old male who initially presented complaining of dyspnea worsening with exertion. Computed tomography imaging was performed showing an extra-pleural mass residing under the left sixth rib. Subsequent core needle biopsy and immunohistochemical staining were performed, and the definitive diagnosis of primary leiomyoma of the posterior mediastinal chest wall. Although extremely rare, this neoplastic condition should be included in your differential diagnosis when diagnostic imaging reveals a benign mass residing in the extra-pleural space, and subsequent biopsy specimens consist of smooth muscle fibers.
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spelling doaj.art-cef5c7c2f0eb46669f4ac50fff6375a32023-11-23T10:36:35ZengMDPI AGCurrent Oncology1198-00521718-77292022-04-012952935294010.3390/curroncol29050240Primary Extra-Pleura Leiomyoma: A Case Report and Literature ReviewAsad Ullah0G. Taylor Patterson1Intisar Ghleilib2Islam A. Elhelf3Nikhil G. Patel4Nagla A. Karim5Department of Pathology, Augusta University, Augusta, GA 30912, USAMedical College of Georgia, Augusta, GA 30912, USADepartment of Pathology, Augusta University, Augusta, GA 30912, USADepartment of Radiology, Augusta University, Augusta, GA 30912, USADepartment of Pathology, Augusta University, Augusta, GA 30912, USADepartment of Medicine, Hematology and Oncology, Augusta University, Augusta, GA 30912, USALeiomyomas are a common type of benign soft tissue tumor arising from smooth muscle, most often occurring within females’ genitourinary and gastrointestinal tract. However, primary leiomyomas of the chest wall residing in the extra-pleural space are an extremely rare subset of leiomyomatous lesion presentation. We present a case of a fifty-two-year-old male who initially presented complaining of dyspnea worsening with exertion. Computed tomography imaging was performed showing an extra-pleural mass residing under the left sixth rib. Subsequent core needle biopsy and immunohistochemical staining were performed, and the definitive diagnosis of primary leiomyoma of the posterior mediastinal chest wall. Although extremely rare, this neoplastic condition should be included in your differential diagnosis when diagnostic imaging reveals a benign mass residing in the extra-pleural space, and subsequent biopsy specimens consist of smooth muscle fibers.https://www.mdpi.com/1718-7729/29/5/240pleural tumorleiomyomacomputed tomography
spellingShingle Asad Ullah
G. Taylor Patterson
Intisar Ghleilib
Islam A. Elhelf
Nikhil G. Patel
Nagla A. Karim
Primary Extra-Pleura Leiomyoma: A Case Report and Literature Review
Current Oncology
pleural tumor
leiomyoma
computed tomography
title Primary Extra-Pleura Leiomyoma: A Case Report and Literature Review
title_full Primary Extra-Pleura Leiomyoma: A Case Report and Literature Review
title_fullStr Primary Extra-Pleura Leiomyoma: A Case Report and Literature Review
title_full_unstemmed Primary Extra-Pleura Leiomyoma: A Case Report and Literature Review
title_short Primary Extra-Pleura Leiomyoma: A Case Report and Literature Review
title_sort primary extra pleura leiomyoma a case report and literature review
topic pleural tumor
leiomyoma
computed tomography
url https://www.mdpi.com/1718-7729/29/5/240
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