Total and ionized serum magnesium and calcium levels during magnesium sulfate administration for preterm labor
ObjectiveThis study aimed to estimate the association between total and ionized magnesium, and the changes in serum magnesium and calcium levels in patients with preterm labor during magnesium sulfate (MgSO4) administration.MethodsThe study population included 64 women who were candidates for intrav...
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| Format: | Article |
| Language: | English |
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Korean Society of Obstetrics and Gynecology
2018-01-01
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| Series: | Obstetrics & Gynecology Science |
| Subjects: | |
| Online Access: | http://ogscience.org/upload/pdf/ogs-61-56.pdf |
| _version_ | 1819074745719586816 |
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| author | Won Hee Kim Yoon Ha Kim Yuna An Jong Ho Moon Eun Ji Noh Jong Woon Kim |
| author_facet | Won Hee Kim Yoon Ha Kim Yuna An Jong Ho Moon Eun Ji Noh Jong Woon Kim |
| author_sort | Won Hee Kim |
| collection | DOAJ |
| description | ObjectiveThis study aimed to estimate the association between total and ionized magnesium, and the changes in serum magnesium and calcium levels in patients with preterm labor during magnesium sulfate (MgSO4) administration.MethodsThe study population included 64 women who were candidates for intravenous MgSO4 treatment for preterm labor. Serial blood samples were taken and measured total magnesium (T-Mg), ionized magnesium (I-Mg), total calcium (T-Ca), and ionized calcium (I-Ca) levels every one-week interval (1st, 2nd, 3rd).ResultsThere was no significant difference in T-Mg and I-Mg levels during MgSO4 administration (P>0.05). There was no significant difference in T-Ca and I-Ca levels during MgSO4 administration (P>0.05). Compared before and after administration of MgSO4, T-Mg and I-Mg levels and T-Ca levels were changed allow statistically significant (P<0.05). But, there was no significant difference in the I-Ca serum levels before and after MgSO4 administration (P=0.495). The I-Mg levels for patients with adverse effect were higher than other group but did not reach statistical significance (P>0.05). There was significant correlation between levels of I-Mg and T-Mg (I-Mg=0.395×T-Mg+0.144, P<0.01).ConclusionThere were no significant differences in serum Mg and Ca levels during MgSO4 administration for preterm labor. Compared to the before and after administration of MgSO4, only I-Ca levels were not substantially changed. There are significant correlations between I-Mg and T-Mg levels during administration of MgSO4 and I-Mg level seemed to have more correlation with adverse effect than T-Mg. |
| first_indexed | 2024-12-21T18:14:24Z |
| format | Article |
| id | doaj.art-cefb28e4830c4df3b2b2b2f6365e805a |
| institution | Directory Open Access Journal |
| issn | 2287-8572 2287-8580 |
| language | English |
| last_indexed | 2024-12-21T18:14:24Z |
| publishDate | 2018-01-01 |
| publisher | Korean Society of Obstetrics and Gynecology |
| record_format | Article |
| series | Obstetrics & Gynecology Science |
| spelling | doaj.art-cefb28e4830c4df3b2b2b2f6365e805a2022-12-21T18:54:43ZengKorean Society of Obstetrics and GynecologyObstetrics & Gynecology Science2287-85722287-85802018-01-01611566210.5468/ogs.2018.61.1.56523Total and ionized serum magnesium and calcium levels during magnesium sulfate administration for preterm laborWon Hee Kim0Yoon Ha Kim1Yuna An2Jong Ho Moon3Eun Ji Noh4Jong Woon Kim5Department of Obstetrics and Gynecology, Chonnam National University Medical School, Gwangju, .KoreaDepartment of Obstetrics and Gynecology, Chonnam National University Medical School, Gwangju, .KoreaDepartment of Obstetrics and Gynecology, Chonnam National University Medical School, Gwangju, .KoreaDepartment of Obstetrics and Gynecology, Chonnam National University Medical School, Gwangju, .KoreaDepartment of Obstetrics and Gynecology, Chonnam National University Medical School, Gwangju, .KoreaDepartment of Obstetrics and Gynecology, Chonnam National University Medical School, Gwangju, .KoreaObjectiveThis study aimed to estimate the association between total and ionized magnesium, and the changes in serum magnesium and calcium levels in patients with preterm labor during magnesium sulfate (MgSO4) administration.MethodsThe study population included 64 women who were candidates for intravenous MgSO4 treatment for preterm labor. Serial blood samples were taken and measured total magnesium (T-Mg), ionized magnesium (I-Mg), total calcium (T-Ca), and ionized calcium (I-Ca) levels every one-week interval (1st, 2nd, 3rd).ResultsThere was no significant difference in T-Mg and I-Mg levels during MgSO4 administration (P>0.05). There was no significant difference in T-Ca and I-Ca levels during MgSO4 administration (P>0.05). Compared before and after administration of MgSO4, T-Mg and I-Mg levels and T-Ca levels were changed allow statistically significant (P<0.05). But, there was no significant difference in the I-Ca serum levels before and after MgSO4 administration (P=0.495). The I-Mg levels for patients with adverse effect were higher than other group but did not reach statistical significance (P>0.05). There was significant correlation between levels of I-Mg and T-Mg (I-Mg=0.395×T-Mg+0.144, P<0.01).ConclusionThere were no significant differences in serum Mg and Ca levels during MgSO4 administration for preterm labor. Compared to the before and after administration of MgSO4, only I-Ca levels were not substantially changed. There are significant correlations between I-Mg and T-Mg levels during administration of MgSO4 and I-Mg level seemed to have more correlation with adverse effect than T-Mg.http://ogscience.org/upload/pdf/ogs-61-56.pdfmagnesium sulfatemagnesiumcalciumobstetric labor, premature |
| spellingShingle | Won Hee Kim Yoon Ha Kim Yuna An Jong Ho Moon Eun Ji Noh Jong Woon Kim Total and ionized serum magnesium and calcium levels during magnesium sulfate administration for preterm labor Obstetrics & Gynecology Science magnesium sulfate magnesium calcium obstetric labor, premature |
| title | Total and ionized serum magnesium and calcium levels during magnesium sulfate administration for preterm labor |
| title_full | Total and ionized serum magnesium and calcium levels during magnesium sulfate administration for preterm labor |
| title_fullStr | Total and ionized serum magnesium and calcium levels during magnesium sulfate administration for preterm labor |
| title_full_unstemmed | Total and ionized serum magnesium and calcium levels during magnesium sulfate administration for preterm labor |
| title_short | Total and ionized serum magnesium and calcium levels during magnesium sulfate administration for preterm labor |
| title_sort | total and ionized serum magnesium and calcium levels during magnesium sulfate administration for preterm labor |
| topic | magnesium sulfate magnesium calcium obstetric labor, premature |
| url | http://ogscience.org/upload/pdf/ogs-61-56.pdf |
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