Investigating the electric field distribution in the human brain model induced by a high focality transcranial magnetic coil
Transcranial magnetic stimulation (TMS) is a noninvasive neuromodulation technique for treating various neurological disorders. The geometry of the TMS coil determines the focality, stimulation field strength, and stimulation depth of the induced electric field. In this paper, we introduce a novel c...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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AIP Publishing LLC
2023-10-01
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| Series: | AIP Advances |
| Online Access: | http://dx.doi.org/10.1063/5.0167257 |
| _version_ | 1797634126076968960 |
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| author | Yong Wang Yonghui Yang Yihao Qi Enzhong Gong Haiyang Zhang Liantao Shi Zhengguo Li |
| author_facet | Yong Wang Yonghui Yang Yihao Qi Enzhong Gong Haiyang Zhang Liantao Shi Zhengguo Li |
| author_sort | Yong Wang |
| collection | DOAJ |
| description | Transcranial magnetic stimulation (TMS) is a noninvasive neuromodulation technique for treating various neurological disorders. The geometry of the TMS coil determines the focality, stimulation field strength, and stimulation depth of the induced electric field. In this paper, we introduce a novel coil, named the eccentric folding coil (EFC). We used Sim4Life, a three-dimensional human tissue medical electromagnetic simulation software, and the brain models of the subjects from the population head model repository to conduct finite element simulations of the eccentric folding coil, circular coil, and figure-eight coil, implying that the largest EFC has a focal area of 19.5 cm2 less than the smallest circular coil, and the EFC of any size has a smaller focal area than the figure-8 coil of the same size. Furthermore, we stimulated the model from three directions with the coil and measured the electric field responses of the model, confirming that stimulation varied in different directions. Additionally, we applied EFC to four representative human models and found that the electric field in different subjects’ brains differed by 3.03 mm in stimulation depth and 12.9 cm2 in focal area, suggesting that personalized human head modeling and electromagnetic analysis are essential for TMS treatment. In the future, we will explore using different types of TMS devices for patients with different conditions to achieve more precise and customized treatment. |
| first_indexed | 2024-03-11T12:04:04Z |
| format | Article |
| id | doaj.art-cf00c3ee2e934abbae6f7a7ddafae5ae |
| institution | Directory Open Access Journal |
| issn | 2158-3226 |
| language | English |
| last_indexed | 2024-03-11T12:04:04Z |
| publishDate | 2023-10-01 |
| publisher | AIP Publishing LLC |
| record_format | Article |
| series | AIP Advances |
| spelling | doaj.art-cf00c3ee2e934abbae6f7a7ddafae5ae2023-11-07T17:47:01ZengAIP Publishing LLCAIP Advances2158-32262023-10-011310105211105211-810.1063/5.0167257Investigating the electric field distribution in the human brain model induced by a high focality transcranial magnetic coilYong Wang0Yonghui Yang1Yihao Qi2Enzhong Gong3Haiyang Zhang4Liantao Shi5Zhengguo Li6Institute for Carbon-Neutral-Technology, Shenzhen Polytechnic University, Shenzhen 518055, ChinaSchool of Electronics and Information Engineering, University of Science and Technology Liaoning, Anshan 114051, ChinaSchool of Electronics and Information Engineering, University of Science and Technology Liaoning, Anshan 114051, ChinaInstitute for Carbon-Neutral-Technology, Shenzhen Polytechnic University, Shenzhen 518055, ChinaInstitute for Carbon-Neutral-Technology, Shenzhen Polytechnic University, Shenzhen 518055, ChinaInstitute for Carbon-Neutral-Technology, Shenzhen Polytechnic University, Shenzhen 518055, ChinaInstitute for Carbon-Neutral-Technology, Shenzhen Polytechnic University, Shenzhen 518055, ChinaTranscranial magnetic stimulation (TMS) is a noninvasive neuromodulation technique for treating various neurological disorders. The geometry of the TMS coil determines the focality, stimulation field strength, and stimulation depth of the induced electric field. In this paper, we introduce a novel coil, named the eccentric folding coil (EFC). We used Sim4Life, a three-dimensional human tissue medical electromagnetic simulation software, and the brain models of the subjects from the population head model repository to conduct finite element simulations of the eccentric folding coil, circular coil, and figure-eight coil, implying that the largest EFC has a focal area of 19.5 cm2 less than the smallest circular coil, and the EFC of any size has a smaller focal area than the figure-8 coil of the same size. Furthermore, we stimulated the model from three directions with the coil and measured the electric field responses of the model, confirming that stimulation varied in different directions. Additionally, we applied EFC to four representative human models and found that the electric field in different subjects’ brains differed by 3.03 mm in stimulation depth and 12.9 cm2 in focal area, suggesting that personalized human head modeling and electromagnetic analysis are essential for TMS treatment. In the future, we will explore using different types of TMS devices for patients with different conditions to achieve more precise and customized treatment.http://dx.doi.org/10.1063/5.0167257 |
| spellingShingle | Yong Wang Yonghui Yang Yihao Qi Enzhong Gong Haiyang Zhang Liantao Shi Zhengguo Li Investigating the electric field distribution in the human brain model induced by a high focality transcranial magnetic coil AIP Advances |
| title | Investigating the electric field distribution in the human brain model induced by a high focality transcranial magnetic coil |
| title_full | Investigating the electric field distribution in the human brain model induced by a high focality transcranial magnetic coil |
| title_fullStr | Investigating the electric field distribution in the human brain model induced by a high focality transcranial magnetic coil |
| title_full_unstemmed | Investigating the electric field distribution in the human brain model induced by a high focality transcranial magnetic coil |
| title_short | Investigating the electric field distribution in the human brain model induced by a high focality transcranial magnetic coil |
| title_sort | investigating the electric field distribution in the human brain model induced by a high focality transcranial magnetic coil |
| url | http://dx.doi.org/10.1063/5.0167257 |
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