Optimization of Medium Constituents for the Production of Citric Acid from Waste Glycerol Using the Central Composite Rotatable Design of Experiments

Optimization of Medium Constituents for the Production of Citric Acid from Waste Glycerol Using the Central Composite Rotatable Design of Experiments

Citric acid is currently produced by submerged fermentation of sucrose with the aid of <i>Aspergillus niger</i> mold. Its strains are characterized by a high yield of citric acid biosynthesis and no toxic by-products. Currently, new substrates are sought for production of citric acid by...

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Bibliographic Details
Main Authors: Ewelina Ewa Książek, Małgorzata Janczar-Smuga, Jerzy Jan Pietkiewicz, Ewa Walaszczyk
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Molecules
Subjects:
citric acid
<i>Aspergillus niger</i>
design of experiments
response surface methodology
optimization
glycerol
Online Access:https://www.mdpi.com/1420-3049/28/7/3268

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