Outer membrane vesicle-associated lipase FtlA enhances cellular invasion and virulence in Francisella tularensis LVS

Outer membrane vesicle-associated lipase FtlA enhances cellular invasion and virulence in Francisella tularensis LVS

Francisella tularensis is a highly infectious intracellular pathogen that infects a wide range of host species and causes fatal pneumonic tularemia in humans. ftlA was identified as a potential virulence determinant of the F. tularensis live vaccine strain (LVS) in our previous transposon screen, bu...

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Bibliographic Details
Main Authors: Fei Chen, Guolin Cui, Shuxia Wang, Manoj Kumar Mohan Nair, Lihong He, Xinyi Qi, Xiangmin Han, Hanqi Zhang, Jing-Ren Zhang, Jingliang Su
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Emerging Microbes and Infections
Subjects:
Francisella tularensis
FTL_0430
FtlA
intracellular infection
lipase
outer membrane vesicle
Online Access:https://www.tandfonline.com/doi/10.1038/emi.2017.53

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