Protocatechuic acid inhibits proliferation, migration and inflammatory response in rheumatoid arthritis fibroblast-like synoviocytes

Protocatechuic acid inhibits proliferation, migration and inflammatory response in rheumatoid arthritis fibroblast-like synoviocytes

AbstractRheumatoid arthritis (RA) is a chronic joint inflammatory disease that is closely associated with dysregulation of fibroblast-like synoviocytes (FLSs). Protocatechuic acid (PCA), a phenolic compound of anthocyanins, has been proven to possess anti-inflammatory activity. However, the role of...

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Bibliographic Details
Main Authors: Huiqiang Wu, Jing Wang, Qing Zhao, Yanjie Ding, Bingyi Zhang, Lingli Kong
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Artificial Cells, Nanomedicine, and Biotechnology
Subjects:
Rheumatoid arthritis (RA)
fibroblast-like synoviocytes (FLSs)
PCA
inflammation
NF-κB signalling pathway
Akt/mTOR pathway
Online Access:https://www.tandfonline.com/doi/10.1080/21691401.2020.1776307

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