In-vitro Control of Oral Thrush Causal Organisms Using Medicinal Plants Extracts

Oral hygiene is important to the generality of the human healthcare system. For this, the antifungal activities of the aqueous and ethanol extracts of four medicinal plants of Jatropha curcas (stem), Eucaluptus golbulus (leaves), Vernonia amygdalina (stem) and Zanthoxylum zanthoxyloides (root) were...

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Main Authors: Abosede M. EBABHI, Adedotun A. ADEKUNLE, Yoma I. OGHENERHABOKE
Format: Article
Language:English
Published: Society of Land Measurements and Cadastre from Transylvania (SMTCT) 2019-09-01
Series:Notulae Scientia Biologicae
Subjects:
Online Access:https://www.notulaebiologicae.ro/index.php/nsb/article/view/10443
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author Abosede M. EBABHI
Adedotun A. ADEKUNLE
Yoma I. OGHENERHABOKE
author_facet Abosede M. EBABHI
Adedotun A. ADEKUNLE
Yoma I. OGHENERHABOKE
author_sort Abosede M. EBABHI
collection DOAJ
description Oral hygiene is important to the generality of the human healthcare system. For this, the antifungal activities of the aqueous and ethanol extracts of four medicinal plants of Jatropha curcas (stem), Eucaluptus golbulus (leaves), Vernonia amygdalina (stem) and Zanthoxylum zanthoxyloides (root) were carried out in vitro against three species of Candida associated with oral thrush namely C. albicans, C. glabrata, C. tropicalis using the disc diffusion agar assay. The zones of inhibition varied with the test organisms as well as the extracts. The ethanolic extract of Jatropha curcas showed the highest zone of inhibition of 10.88 ± 0.22 mm against C. albicans while the least zone of inhibition (6.13 ± 0.13 mm) was exhibited by the ethanol extract of Z. zanthoxyloides on C. glabrata. The preliminary phytochemical screening showed the presence of tannin, saponin, alkaloids, flavonoids and reducing sugar in all plant samples. This study can be further used as a foundation for the screening of phytochemical constituents by pharmaceuticals for the control and eradication of oral thrush.
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spelling doaj.art-cf06a92c6aef4c4599fe18ba5058c0372022-12-22T02:06:11ZengSociety of Land Measurements and Cadastre from Transylvania (SMTCT)Notulae Scientia Biologicae2067-32052067-32642019-09-0111310.15835/nsb11310443In-vitro Control of Oral Thrush Causal Organisms Using Medicinal Plants ExtractsAbosede M. EBABHI0Adedotun A. ADEKUNLE1Yoma I. OGHENERHABOKE2University of Lagos, Distance Learning Institute, Akoka, LagosUniversity of Lagos, Faculty of Science, Department of Botany, Akoka, LagosUniversity of Lagos, Faculty of Science, Department of Botany, Akoka, LagosOral hygiene is important to the generality of the human healthcare system. For this, the antifungal activities of the aqueous and ethanol extracts of four medicinal plants of Jatropha curcas (stem), Eucaluptus golbulus (leaves), Vernonia amygdalina (stem) and Zanthoxylum zanthoxyloides (root) were carried out in vitro against three species of Candida associated with oral thrush namely C. albicans, C. glabrata, C. tropicalis using the disc diffusion agar assay. The zones of inhibition varied with the test organisms as well as the extracts. The ethanolic extract of Jatropha curcas showed the highest zone of inhibition of 10.88 ± 0.22 mm against C. albicans while the least zone of inhibition (6.13 ± 0.13 mm) was exhibited by the ethanol extract of Z. zanthoxyloides on C. glabrata. The preliminary phytochemical screening showed the presence of tannin, saponin, alkaloids, flavonoids and reducing sugar in all plant samples. This study can be further used as a foundation for the screening of phytochemical constituents by pharmaceuticals for the control and eradication of oral thrush.https://www.notulaebiologicae.ro/index.php/nsb/article/view/10443Candida spp.; medicinal plants; mouth swab; oral thrush; phytochemicals
spellingShingle Abosede M. EBABHI
Adedotun A. ADEKUNLE
Yoma I. OGHENERHABOKE
In-vitro Control of Oral Thrush Causal Organisms Using Medicinal Plants Extracts
Notulae Scientia Biologicae
Candida spp.; medicinal plants; mouth swab; oral thrush; phytochemicals
title In-vitro Control of Oral Thrush Causal Organisms Using Medicinal Plants Extracts
title_full In-vitro Control of Oral Thrush Causal Organisms Using Medicinal Plants Extracts
title_fullStr In-vitro Control of Oral Thrush Causal Organisms Using Medicinal Plants Extracts
title_full_unstemmed In-vitro Control of Oral Thrush Causal Organisms Using Medicinal Plants Extracts
title_short In-vitro Control of Oral Thrush Causal Organisms Using Medicinal Plants Extracts
title_sort in vitro control of oral thrush causal organisms using medicinal plants extracts
topic Candida spp.; medicinal plants; mouth swab; oral thrush; phytochemicals
url https://www.notulaebiologicae.ro/index.php/nsb/article/view/10443
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