A randomised controlled trial to examine the effects of cinacalcet on bone and cardiovascular parameters in haemodialysis patients with advanced secondary hyperparathyroidism

A randomised controlled trial to examine the effects of cinacalcet on bone and cardiovascular parameters in haemodialysis patients with advanced secondary hyperparathyroidism

Abstract Background Secondary hyperparathyroidism may lead to increased cardiovascular risk. The use of cinacalcet may improve bone and cardiovascular health with improved parathormone (PTH) and phosphate control. Methods This is an open-label prospective randomised controlled trial to compare progr...

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Bibliographic Details
Main Authors: Helen Eddington, Rajkumar Chinnadurai, Helen Alderson, Sara T. Ibrahim, Constantina Chrysochou, Darren Green, Ibi Erekosima, Alastair Hutchison, Abdalla Bubtana, Janet Hegarty, Philip A. Kalra
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Nephrology
Subjects:
Chronic kidney disease-mineral bone disorder (CKD-MBD)
Cinacalcet
Secondary hyperparathyroidism
Left ventricular mass index (LVMI)
Parathormone (PTH)
Online Access:https://doi.org/10.1186/s12882-021-02312-2

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