The Mechanisms of Polysaccharides from Tonic Chinese Herbal Medicine on the Enhancement Immune Function: A Review

Tonic Chinese herbal medicine is a type of traditional Chinese medicine, and its primary function is to restore the body’s lost nutrients, improve activity levels, increase disease resistance, and alleviate physical exhaustion. The body’s immunity can be strengthened by its polysaccharide components...

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Main Authors: Zhiyi Xie, Ninghua Jiang, Minqiu Lin, Xinglishang He, Bo Li, Yingjie Dong, Suhong Chen, Guiyuan Lv
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/21/7355
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author Zhiyi Xie
Ninghua Jiang
Minqiu Lin
Xinglishang He
Bo Li
Yingjie Dong
Suhong Chen
Guiyuan Lv
author_facet Zhiyi Xie
Ninghua Jiang
Minqiu Lin
Xinglishang He
Bo Li
Yingjie Dong
Suhong Chen
Guiyuan Lv
author_sort Zhiyi Xie
collection DOAJ
description Tonic Chinese herbal medicine is a type of traditional Chinese medicine, and its primary function is to restore the body’s lost nutrients, improve activity levels, increase disease resistance, and alleviate physical exhaustion. The body’s immunity can be strengthened by its polysaccharide components, which also have a potent immune-system-protecting effect. Several studies have demonstrated that tonic Chinese herbal medicine polysaccharides can improve the body’s immune response to tumor cells, viruses, bacteria, and other harmful substances. However, the regulatory mechanisms by which various polysaccharides used in tonic Chinese herbal medicine enhance immune function vary. This study examines the regulatory effects of different tonic Chinese herbal medicine polysaccharides on immune organs, immune cells, and immune-related cytokines. It explores the immune response mechanism to understand the similarities and differences in the effects of tonic Chinese herbal medicine polysaccharides on immune function and to lay the foundation for the future development of tonic Chinese herbal medicine polysaccharide products.
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spelling doaj.art-cf0945ec0cfd434f8d32b1cb3c0ca8882023-11-10T15:08:44ZengMDPI AGMolecules1420-30492023-10-012821735510.3390/molecules28217355The Mechanisms of Polysaccharides from Tonic Chinese Herbal Medicine on the Enhancement Immune Function: A ReviewZhiyi Xie0Ninghua Jiang1Minqiu Lin2Xinglishang He3Bo Li4Yingjie Dong5Suhong Chen6Guiyuan Lv7College of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou 310053, ChinaThe Second Affiliated Hospital of Jiaxing University, Jiaxing 314000, ChinaCollaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Huzhou 313200, ChinaCollaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Huzhou 313200, ChinaCollaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Huzhou 313200, ChinaCollege of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou 310053, ChinaCollege of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou 310053, ChinaCollege of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou 310053, ChinaTonic Chinese herbal medicine is a type of traditional Chinese medicine, and its primary function is to restore the body’s lost nutrients, improve activity levels, increase disease resistance, and alleviate physical exhaustion. The body’s immunity can be strengthened by its polysaccharide components, which also have a potent immune-system-protecting effect. Several studies have demonstrated that tonic Chinese herbal medicine polysaccharides can improve the body’s immune response to tumor cells, viruses, bacteria, and other harmful substances. However, the regulatory mechanisms by which various polysaccharides used in tonic Chinese herbal medicine enhance immune function vary. This study examines the regulatory effects of different tonic Chinese herbal medicine polysaccharides on immune organs, immune cells, and immune-related cytokines. It explores the immune response mechanism to understand the similarities and differences in the effects of tonic Chinese herbal medicine polysaccharides on immune function and to lay the foundation for the future development of tonic Chinese herbal medicine polysaccharide products.https://www.mdpi.com/1420-3049/28/21/7355traditional Chinese medicinepolysaccharidesautoimmunitymechanisms of action
spellingShingle Zhiyi Xie
Ninghua Jiang
Minqiu Lin
Xinglishang He
Bo Li
Yingjie Dong
Suhong Chen
Guiyuan Lv
The Mechanisms of Polysaccharides from Tonic Chinese Herbal Medicine on the Enhancement Immune Function: A Review
Molecules
traditional Chinese medicine
polysaccharides
autoimmunity
mechanisms of action
title The Mechanisms of Polysaccharides from Tonic Chinese Herbal Medicine on the Enhancement Immune Function: A Review
title_full The Mechanisms of Polysaccharides from Tonic Chinese Herbal Medicine on the Enhancement Immune Function: A Review
title_fullStr The Mechanisms of Polysaccharides from Tonic Chinese Herbal Medicine on the Enhancement Immune Function: A Review
title_full_unstemmed The Mechanisms of Polysaccharides from Tonic Chinese Herbal Medicine on the Enhancement Immune Function: A Review
title_short The Mechanisms of Polysaccharides from Tonic Chinese Herbal Medicine on the Enhancement Immune Function: A Review
title_sort mechanisms of polysaccharides from tonic chinese herbal medicine on the enhancement immune function a review
topic traditional Chinese medicine
polysaccharides
autoimmunity
mechanisms of action
url https://www.mdpi.com/1420-3049/28/21/7355
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