Controlled in vivo Bone Formation and Vascularization Using Ultrasound-Triggered Release of Recombinant Vascular Endothelial Growth Factor From Poly(D,L-lactic-co-glycolicacid) Microbubbles

Controlled in vivo Bone Formation and Vascularization Using Ultrasound-Triggered Release of Recombinant Vascular Endothelial Growth Factor From Poly(D,L-lactic-co-glycolicacid) Microbubbles

Bone defects are challenging to treat in musculoskeletal system due to the lack of vascularization. Biomaterials with internal vascularization ability and osteoinduction bioactivity are promising strategies for orthopedic applications. Vascular endothelial growth factor (VEGF) has been widely used f...

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Dades bibliogràfiques
Autors principals:	Yong Gong, Songjian Li, Wei Zeng, Jianing Yu, Yan Chen, Bo Yu
Format:	Article
Idioma:	English
Publicat:	Frontiers Media S.A. 2019-04-01
Col·lecció:	Frontiers in Pharmacology
Matèries:	bone defect vascular endothelial growth factor angiogenesis ultrasound osteogenesis
Accés en línia:	https://www.frontiersin.org/article/10.3389/fphar.2019.00413/full

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