A new scoring system for Covid-19 in patients on hemodialysis: Modified Early Warning score

Introduction. At the very beginning of the Corona virus epidemic there was not enough data on whether hemodialysis patients have a higher risk for Corona virus infection and which factors may affect the severity of clinical picture. Objective. The aim of the study was to determine the significance o...

Full description

Bibliographic Details
Main Authors: Stolić Radojica V., Bukumirić Dragica, Jovanović Milena Z., Nikolić Tomislav S., Labudović Tatjana, Mitrović Vekoslav, Bulatović Kristina M., Sovtić Saša, Miljković Dušica, Balović Aleksandra D., Krivcević Roksanda N., Jovanović Sanja M.
Format: Article
Language:English
Published: Medicinski fakultet Priština, Društvo lekara Kosova i Metohije Srpskog lekarskog društva 2021-01-01
Series:Praxis Medica
Subjects:
Online Access:https://scindeks-clanci.ceon.rs/data/pdf/0350-8773/2021/0350-87732101001S.pdf
_version_ 1818995809868316672
author Stolić Radojica V.
Bukumirić Dragica
Jovanović Milena Z.
Nikolić Tomislav S.
Labudović Tatjana
Mitrović Vekoslav
Bulatović Kristina M.
Sovtić Saša
Miljković Dušica
Balović Aleksandra D.
Krivcević Roksanda N.
Jovanović Sanja M.
author_facet Stolić Radojica V.
Bukumirić Dragica
Jovanović Milena Z.
Nikolić Tomislav S.
Labudović Tatjana
Mitrović Vekoslav
Bulatović Kristina M.
Sovtić Saša
Miljković Dušica
Balović Aleksandra D.
Krivcević Roksanda N.
Jovanović Sanja M.
author_sort Stolić Radojica V.
collection DOAJ
description Introduction. At the very beginning of the Corona virus epidemic there was not enough data on whether hemodialysis patients have a higher risk for Corona virus infection and which factors may affect the severity of clinical picture. Objective. The aim of the study was to determine the significance of the Modified Early Warning Assessment (MEWS) score for the assessment of coronavirus disease exacerbation. Methods. The research was conducted in COVID dialysis, as a retrospective, descriptive-analytical study, at the University Clinical Center Kragujevac, Serbia, which was organized ad-hoc for treatment of SARS-Cov-2 infection positive patients, which are transfered from Center for Hemodialysis "Ćuprija". They were evaluated routine laboratory findings, demographic and gender structure, arterial blood pressure, presence of comorbidities and residual diuresis, duration of dialysis, radiological evaluation of lungs, determination of MEWS score were the parameters that were monitored. The results were monitored on admission and and in the end of treatment. Results. A statistically significant difference was registered in serum lactate dehydrogenase concentration (486 ± 107.62 vs. 423.7 ± 92.4 U/L); p = 0.022 and absolute monocyte count (0.46 ± 0.15 vs. 0.67 ± 0.34 x 103; p = 0.008). The significant increase in MEWS score was also found (b = 0.017; p = 0.030). There was a positive correlation between increase of MEWS score and age (b = 0.027; p = 0.002) and arterial hypertension as a concomitant comorbidity (b = 0.700; p = 0.033). Conclusion. In the observed period, there was a significant increase in the degree of MEWS score of dialysis patients who had SARS-Cov-2 infection.
first_indexed 2024-12-20T21:19:45Z
format Article
id doaj.art-cf0fe28d6c58459291ac36a019277079
institution Directory Open Access Journal
issn 0350-8773
2560-3310
language English
last_indexed 2024-12-20T21:19:45Z
publishDate 2021-01-01
publisher Medicinski fakultet Priština, Društvo lekara Kosova i Metohije Srpskog lekarskog društva
record_format Article
series Praxis Medica
spelling doaj.art-cf0fe28d6c58459291ac36a0192770792022-12-21T19:26:19ZengMedicinski fakultet Priština, Društvo lekara Kosova i Metohije Srpskog lekarskog društvaPraxis Medica0350-87732560-33102021-01-01501-21610.5937/pramed2102001S0350-87732101001SA new scoring system for Covid-19 in patients on hemodialysis: Modified Early Warning scoreStolić Radojica V.0https://orcid.org/0000-0002-6215-9258Bukumirić Dragica1Jovanović Milena Z.2Nikolić Tomislav S.3Labudović Tatjana4Mitrović Vekoslav5Bulatović Kristina M.6Sovtić Saša7Miljković Dušica8Balović Aleksandra D.9Krivcević Roksanda N.10Jovanović Sanja M.11University of Kragujevac, Faculty of Medical Sciences, Department of Internal Medicine, Kragujevac, SerbiaPrimary Health Care Center, Department of Planning, Analysing and Statistics, Pancevo, SerbiaClinical Center Kragujevac, Center for Nephrology and Dialysis, Kragujevac, SerbiaUniversity of Kragujevac, Faculty of Medical Sciences, Department of Internal Medicine, Kragujevac, SerbiaClinical Center Kragujevac, Center for Nephrology and Dialysis, Kragujevac, SerbiaUniversity of East Sarajevo, Faculty of Medicine Foca, Foca, Republika Srpska, Bosnia and HerzegovinaUniversity of Pristina/K. Mitrovica, Medical Faculty, Pristina/K. Mitrovica, SerbiaUniversity of Pristina/K. Mitrovica, Medical Faculty, Pristina/K. Mitrovica, SerbiaUniversity of Pristina/K. Mitrovica, Medical Faculty, Pristina/K. Mitrovica, SerbiaUniversity of Pristina/K. Mitrovica, Medical Faculty, Pristina/K. Mitrovica, SerbiaUniversity of Pristina/K. Mitrovica, Medical Faculty, Pristina/K. Mitrovica, SerbiaUniversity of Pristina/K. Mitrovica, Medical Faculty, Pristina/K. Mitrovica, SerbiaIntroduction. At the very beginning of the Corona virus epidemic there was not enough data on whether hemodialysis patients have a higher risk for Corona virus infection and which factors may affect the severity of clinical picture. Objective. The aim of the study was to determine the significance of the Modified Early Warning Assessment (MEWS) score for the assessment of coronavirus disease exacerbation. Methods. The research was conducted in COVID dialysis, as a retrospective, descriptive-analytical study, at the University Clinical Center Kragujevac, Serbia, which was organized ad-hoc for treatment of SARS-Cov-2 infection positive patients, which are transfered from Center for Hemodialysis "Ćuprija". They were evaluated routine laboratory findings, demographic and gender structure, arterial blood pressure, presence of comorbidities and residual diuresis, duration of dialysis, radiological evaluation of lungs, determination of MEWS score were the parameters that were monitored. The results were monitored on admission and and in the end of treatment. Results. A statistically significant difference was registered in serum lactate dehydrogenase concentration (486 ± 107.62 vs. 423.7 ± 92.4 U/L); p = 0.022 and absolute monocyte count (0.46 ± 0.15 vs. 0.67 ± 0.34 x 103; p = 0.008). The significant increase in MEWS score was also found (b = 0.017; p = 0.030). There was a positive correlation between increase of MEWS score and age (b = 0.027; p = 0.002) and arterial hypertension as a concomitant comorbidity (b = 0.700; p = 0.033). Conclusion. In the observed period, there was a significant increase in the degree of MEWS score of dialysis patients who had SARS-Cov-2 infection.https://scindeks-clanci.ceon.rs/data/pdf/0350-8773/2021/0350-87732101001S.pdfsars-cov-2 infectionhemodialysismews scorepredictorworsening
spellingShingle Stolić Radojica V.
Bukumirić Dragica
Jovanović Milena Z.
Nikolić Tomislav S.
Labudović Tatjana
Mitrović Vekoslav
Bulatović Kristina M.
Sovtić Saša
Miljković Dušica
Balović Aleksandra D.
Krivcević Roksanda N.
Jovanović Sanja M.
A new scoring system for Covid-19 in patients on hemodialysis: Modified Early Warning score
Praxis Medica
sars-cov-2 infection
hemodialysis
mews score
predictor
worsening
title A new scoring system for Covid-19 in patients on hemodialysis: Modified Early Warning score
title_full A new scoring system for Covid-19 in patients on hemodialysis: Modified Early Warning score
title_fullStr A new scoring system for Covid-19 in patients on hemodialysis: Modified Early Warning score
title_full_unstemmed A new scoring system for Covid-19 in patients on hemodialysis: Modified Early Warning score
title_short A new scoring system for Covid-19 in patients on hemodialysis: Modified Early Warning score
title_sort new scoring system for covid 19 in patients on hemodialysis modified early warning score
topic sars-cov-2 infection
hemodialysis
mews score
predictor
worsening
url https://scindeks-clanci.ceon.rs/data/pdf/0350-8773/2021/0350-87732101001S.pdf
work_keys_str_mv AT stolicradojicav anewscoringsystemforcovid19inpatientsonhemodialysismodifiedearlywarningscore
AT bukumiricdragica anewscoringsystemforcovid19inpatientsonhemodialysismodifiedearlywarningscore
AT jovanovicmilenaz anewscoringsystemforcovid19inpatientsonhemodialysismodifiedearlywarningscore
AT nikolictomislavs anewscoringsystemforcovid19inpatientsonhemodialysismodifiedearlywarningscore
AT labudovictatjana anewscoringsystemforcovid19inpatientsonhemodialysismodifiedearlywarningscore
AT mitrovicvekoslav anewscoringsystemforcovid19inpatientsonhemodialysismodifiedearlywarningscore
AT bulatovickristinam anewscoringsystemforcovid19inpatientsonhemodialysismodifiedearlywarningscore
AT sovticsasa anewscoringsystemforcovid19inpatientsonhemodialysismodifiedearlywarningscore
AT miljkovicdusica anewscoringsystemforcovid19inpatientsonhemodialysismodifiedearlywarningscore
AT balovicaleksandrad anewscoringsystemforcovid19inpatientsonhemodialysismodifiedearlywarningscore
AT krivcevicroksandan anewscoringsystemforcovid19inpatientsonhemodialysismodifiedearlywarningscore
AT jovanovicsanjam anewscoringsystemforcovid19inpatientsonhemodialysismodifiedearlywarningscore
AT stolicradojicav newscoringsystemforcovid19inpatientsonhemodialysismodifiedearlywarningscore
AT bukumiricdragica newscoringsystemforcovid19inpatientsonhemodialysismodifiedearlywarningscore
AT jovanovicmilenaz newscoringsystemforcovid19inpatientsonhemodialysismodifiedearlywarningscore
AT nikolictomislavs newscoringsystemforcovid19inpatientsonhemodialysismodifiedearlywarningscore
AT labudovictatjana newscoringsystemforcovid19inpatientsonhemodialysismodifiedearlywarningscore
AT mitrovicvekoslav newscoringsystemforcovid19inpatientsonhemodialysismodifiedearlywarningscore
AT bulatovickristinam newscoringsystemforcovid19inpatientsonhemodialysismodifiedearlywarningscore
AT sovticsasa newscoringsystemforcovid19inpatientsonhemodialysismodifiedearlywarningscore
AT miljkovicdusica newscoringsystemforcovid19inpatientsonhemodialysismodifiedearlywarningscore
AT balovicaleksandrad newscoringsystemforcovid19inpatientsonhemodialysismodifiedearlywarningscore
AT krivcevicroksandan newscoringsystemforcovid19inpatientsonhemodialysismodifiedearlywarningscore
AT jovanovicsanjam newscoringsystemforcovid19inpatientsonhemodialysismodifiedearlywarningscore