Nucleotide-level prediction of CircRNA-protein binding based on fully convolutional neural network

Nucleotide-level prediction of CircRNA-protein binding based on fully convolutional neural network

Introduction: CircRNA-protein binding plays a critical role in complex biological activity and disease. Various deep learning-based algorithms have been proposed to identify CircRNA-protein binding sites. These methods predict whether the CircRNA sequence includes protein binding sites from the sequ...

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Bibliographic Details
Main Authors: Zhen Shen, Wei Liu, ShuJun Zhao, QinHu Zhang, SiGuo Wang, Lin Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Genetics
Subjects:
CircRNA-protein binding sites prediction
deep learning
fully convolutional neural networks
hard negative mining loss
nucleotide-level prediction
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1283404/full

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