Ocular development in children with unilateral congenital cataract and persistent fetal vasculature
AIM: To investigate the ocular development of patients who had unilateral congenital cataract (CC) combined with persistent fetal vasculature (PFV). METHODS: This cross-sectional, observational study included patients who had unilateral CC and PFV and those with isolated unilateral CC. Axial length...
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2022-03-01
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| Series: | International Journal of Ophthalmology |
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| Online Access: | http://ies.ijo.cn/en_publish/2022/3/20220309.pdf |
| _version_ | 1819125623825629184 |
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| author | Shu-Yi Zhang Hui Chen Jing-Hui Wang Wan Chen Qi-Wei Wang Jing-Jing Chen Xiao-Shan Lin Zhuo-Ling Lin Duo-Ru Lin Hao-Tian Lin Wei-Rong Chen |
| author_facet | Shu-Yi Zhang Hui Chen Jing-Hui Wang Wan Chen Qi-Wei Wang Jing-Jing Chen Xiao-Shan Lin Zhuo-Ling Lin Duo-Ru Lin Hao-Tian Lin Wei-Rong Chen |
| author_sort | Shu-Yi Zhang |
| collection | DOAJ |
| description | AIM: To investigate the ocular development of patients who had unilateral congenital cataract (CC) combined with persistent fetal vasculature (PFV). METHODS: This cross-sectional, observational study included patients who had unilateral CC and PFV and those with isolated unilateral CC. Axial length (AL), keratometry, anterior chamber depth (ACD), lens thickness, and vitreous length were obtained. The ocular biometric parameters of the affected eyes of patients with CC and PFV were compared with the fellow eyes and with the affected eyes of patients with isolated CC. RESULTS: A total of 110 patients were included and divided into 4 groups: group 1 (18 patients with CC and PFV, <24mo), group 2 (22 patients with CC and PFV, ≥24mo), group 3 (35 patients with CC, <24mo), and group 4 (35 patients with CC, ≥24mo). The ALs of the affected eyes were shorter than those of the fellow eyes in group 1 (20.02±1.06 vs 20.66±0.63 mm, P=0.025). While the ALs of the affected eyes were longer than those of the fellow eyes in group 2 (23.18±2.00 vs 22.31±1.06 mm, P=0.044) and group 4 (22.64±1.80 vs 22.02±1.01 mm, P=0.033). The keratometries of the affected eyes were steeper than those of the fellow eyes in group 2 (44.78±1.66 vs 43.83±1.38 D, P=0.041) and group 4 (43.76±1.91 vs 43.34±1.46 D, P=0.043). No difference of ACDs between two eyes was found in all groups (all P>0.05). CONCLUSION: Compared with the fellow eyes, the ALs of the eyes with unilateral CC and PFV are shorter in patients younger than 24mo and longer in those older than 24mo; the keratometries of the eyes with unilateral CC and PFV are steeper in patients older than 24mo and similar with those younger than 24mo. These findings provide further understanding of ocular development in patients with both CC and PFV. |
| first_indexed | 2024-12-22T07:43:05Z |
| format | Article |
| id | doaj.art-cf1175c9d5e34285bd3c7cb900f096d0 |
| institution | Directory Open Access Journal |
| issn | 2222-3959 2227-4898 |
| language | English |
| last_indexed | 2024-12-22T07:43:05Z |
| publishDate | 2022-03-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | International Journal of Ophthalmology |
| spelling | doaj.art-cf1175c9d5e34285bd3c7cb900f096d02022-12-21T18:33:41ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982022-03-0115342643110.18240/ijo.2022.03.0920220309Ocular development in children with unilateral congenital cataract and persistent fetal vasculatureShu-Yi Zhang0Hui Chen1Jing-Hui Wang2Wan Chen3Qi-Wei Wang4Jing-Jing Chen5Xiao-Shan Lin6Zhuo-Ling Lin7Duo-Ru Lin8Hao-Tian Lin9Wei-Rong Chen10Wei-Rong Chen, Hao-Tian Lin, and Duo-Ru Lin. Zhongshan Ophthalmic Center, Xian Lie South Road 54#, Guangzhou 510060, Guangdong Province, China. chenwr_q@aliyun.com; gddlht@aliyun.com; lindr5@mail.sysu.edu.cnState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China; Center for Precision Medicine, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, ChinaAIM: To investigate the ocular development of patients who had unilateral congenital cataract (CC) combined with persistent fetal vasculature (PFV). METHODS: This cross-sectional, observational study included patients who had unilateral CC and PFV and those with isolated unilateral CC. Axial length (AL), keratometry, anterior chamber depth (ACD), lens thickness, and vitreous length were obtained. The ocular biometric parameters of the affected eyes of patients with CC and PFV were compared with the fellow eyes and with the affected eyes of patients with isolated CC. RESULTS: A total of 110 patients were included and divided into 4 groups: group 1 (18 patients with CC and PFV, <24mo), group 2 (22 patients with CC and PFV, ≥24mo), group 3 (35 patients with CC, <24mo), and group 4 (35 patients with CC, ≥24mo). The ALs of the affected eyes were shorter than those of the fellow eyes in group 1 (20.02±1.06 vs 20.66±0.63 mm, P=0.025). While the ALs of the affected eyes were longer than those of the fellow eyes in group 2 (23.18±2.00 vs 22.31±1.06 mm, P=0.044) and group 4 (22.64±1.80 vs 22.02±1.01 mm, P=0.033). The keratometries of the affected eyes were steeper than those of the fellow eyes in group 2 (44.78±1.66 vs 43.83±1.38 D, P=0.041) and group 4 (43.76±1.91 vs 43.34±1.46 D, P=0.043). No difference of ACDs between two eyes was found in all groups (all P>0.05). CONCLUSION: Compared with the fellow eyes, the ALs of the eyes with unilateral CC and PFV are shorter in patients younger than 24mo and longer in those older than 24mo; the keratometries of the eyes with unilateral CC and PFV are steeper in patients older than 24mo and similar with those younger than 24mo. These findings provide further understanding of ocular development in patients with both CC and PFV.http://ies.ijo.cn/en_publish/2022/3/20220309.pdfocular developmentcongenital cataractpersistent fetal vasculatureaxial lengthkeratometry |
| spellingShingle | Shu-Yi Zhang Hui Chen Jing-Hui Wang Wan Chen Qi-Wei Wang Jing-Jing Chen Xiao-Shan Lin Zhuo-Ling Lin Duo-Ru Lin Hao-Tian Lin Wei-Rong Chen Ocular development in children with unilateral congenital cataract and persistent fetal vasculature International Journal of Ophthalmology ocular development congenital cataract persistent fetal vasculature axial length keratometry |
| title | Ocular development in children with unilateral congenital cataract and persistent fetal vasculature |
| title_full | Ocular development in children with unilateral congenital cataract and persistent fetal vasculature |
| title_fullStr | Ocular development in children with unilateral congenital cataract and persistent fetal vasculature |
| title_full_unstemmed | Ocular development in children with unilateral congenital cataract and persistent fetal vasculature |
| title_short | Ocular development in children with unilateral congenital cataract and persistent fetal vasculature |
| title_sort | ocular development in children with unilateral congenital cataract and persistent fetal vasculature |
| topic | ocular development congenital cataract persistent fetal vasculature axial length keratometry |
| url | http://ies.ijo.cn/en_publish/2022/3/20220309.pdf |
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