Non-Invasive Electrochemical Biosensors Operating in Human Physiological Fluids

Non-invasive healthcare technologies are an important part of research and development nowadays due to the low cost and convenience offered to both healthcare receivers and providers. This work overviews the recent advances in the field of non-invasive electrochemical biosensors operating in secrete...

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Main Authors: Magnus Falk, Carolin Psotta, Stefan Cirovic, Sergey Shleev
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/20/21/6352
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author Magnus Falk
Carolin Psotta
Stefan Cirovic
Sergey Shleev
author_facet Magnus Falk
Carolin Psotta
Stefan Cirovic
Sergey Shleev
author_sort Magnus Falk
collection DOAJ
description Non-invasive healthcare technologies are an important part of research and development nowadays due to the low cost and convenience offered to both healthcare receivers and providers. This work overviews the recent advances in the field of non-invasive electrochemical biosensors operating in secreted human physiological fluids, viz. tears, sweat, saliva, and urine. Described electrochemical devices are based on different electrochemical techniques, viz. amperometry, coulometry, cyclic voltammetry, and impedance spectroscopy. Challenges that confront researchers in this exciting area and key requirements for biodevices are discussed. It is concluded that the field of non-invasive sensing of biomarkers in bodily fluid is highly convoluted. Nonetheless, if the drawbacks are appropriately addressed, and the pitfalls are adroitly circumvented, the approach will most certainly disrupt current clinical and self-monitoring practices.
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spelling doaj.art-cf1362c903d94bb1b279debeeccefb3d2023-11-20T20:06:55ZengMDPI AGSensors1424-82202020-11-012021635210.3390/s20216352Non-Invasive Electrochemical Biosensors Operating in Human Physiological FluidsMagnus Falk0Carolin Psotta1Stefan Cirovic2Sergey Shleev3Department of Biomedical Science, Faculty of Health and Society, and Biofilms—Research Center for Biointerfaces, Malmö University, 20506 Malmö, SwedenDepartment of Biomedical Science, Faculty of Health and Society, and Biofilms—Research Center for Biointerfaces, Malmö University, 20506 Malmö, SwedenDepartment of Biomedical Science, Faculty of Health and Society, and Biofilms—Research Center for Biointerfaces, Malmö University, 20506 Malmö, SwedenDepartment of Biomedical Science, Faculty of Health and Society, and Biofilms—Research Center for Biointerfaces, Malmö University, 20506 Malmö, SwedenNon-invasive healthcare technologies are an important part of research and development nowadays due to the low cost and convenience offered to both healthcare receivers and providers. This work overviews the recent advances in the field of non-invasive electrochemical biosensors operating in secreted human physiological fluids, viz. tears, sweat, saliva, and urine. Described electrochemical devices are based on different electrochemical techniques, viz. amperometry, coulometry, cyclic voltammetry, and impedance spectroscopy. Challenges that confront researchers in this exciting area and key requirements for biodevices are discussed. It is concluded that the field of non-invasive sensing of biomarkers in bodily fluid is highly convoluted. Nonetheless, if the drawbacks are appropriately addressed, and the pitfalls are adroitly circumvented, the approach will most certainly disrupt current clinical and self-monitoring practices.https://www.mdpi.com/1424-8220/20/21/6352non-invasive biosensorshuman physiological fluidstearssweatsalivaurine
spellingShingle Magnus Falk
Carolin Psotta
Stefan Cirovic
Sergey Shleev
Non-Invasive Electrochemical Biosensors Operating in Human Physiological Fluids
Sensors
non-invasive biosensors
human physiological fluids
tears
sweat
saliva
urine
title Non-Invasive Electrochemical Biosensors Operating in Human Physiological Fluids
title_full Non-Invasive Electrochemical Biosensors Operating in Human Physiological Fluids
title_fullStr Non-Invasive Electrochemical Biosensors Operating in Human Physiological Fluids
title_full_unstemmed Non-Invasive Electrochemical Biosensors Operating in Human Physiological Fluids
title_short Non-Invasive Electrochemical Biosensors Operating in Human Physiological Fluids
title_sort non invasive electrochemical biosensors operating in human physiological fluids
topic non-invasive biosensors
human physiological fluids
tears
sweat
saliva
urine
url https://www.mdpi.com/1424-8220/20/21/6352
work_keys_str_mv AT magnusfalk noninvasiveelectrochemicalbiosensorsoperatinginhumanphysiologicalfluids
AT carolinpsotta noninvasiveelectrochemicalbiosensorsoperatinginhumanphysiologicalfluids
AT stefancirovic noninvasiveelectrochemicalbiosensorsoperatinginhumanphysiologicalfluids
AT sergeyshleev noninvasiveelectrochemicalbiosensorsoperatinginhumanphysiologicalfluids