Seronegative <i>Myasthenia Gravis</i> with Concomitant SARS-CoV-2 Infection in a Dog
<i>Myasthenia gravis</i> (MG) is a disorder of neuromuscular transmission affecting the neuromuscular junction. The majority of cases involve an autoimmune attack against AChR, but a limited number of patients are seronegative for AChR antibodies. Viral infection is incriminated as a tri...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-06-01
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| Series: | Veterinary Sciences |
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| Online Access: | https://www.mdpi.com/2306-7381/9/7/318 |
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| author | Mihai Musteata Denis-Gabriel Borcea Andreea Despa Raluca Ștefănescu Larisa Ivănescu Luminița Diana Hrițcu Radu Andrei Baisan Radu Lăcătuș Gheorghe Solcan |
| author_facet | Mihai Musteata Denis-Gabriel Borcea Andreea Despa Raluca Ștefănescu Larisa Ivănescu Luminița Diana Hrițcu Radu Andrei Baisan Radu Lăcătuș Gheorghe Solcan |
| author_sort | Mihai Musteata |
| collection | DOAJ |
| description | <i>Myasthenia gravis</i> (MG) is a disorder of neuromuscular transmission affecting the neuromuscular junction. The majority of cases involve an autoimmune attack against AChR, but a limited number of patients are seronegative for AChR antibodies. Viral infection is incriminated as a trigger for MG occurrence, and in a limited number of reports, infection with SARS-CoV-2 was found to be associated with MG expression in humans. In this report, we describe case of seronegative generalized MG in a 2-year-old crossbred female dog associated with SARS-CoV-2 infection due to close exposure to an infected owner. |
| first_indexed | 2024-03-09T05:43:33Z |
| format | Article |
| id | doaj.art-cf17c3cf6d9b422f9962b9dc82e3b2d7 |
| institution | Directory Open Access Journal |
| issn | 2306-7381 |
| language | English |
| last_indexed | 2024-03-09T05:43:33Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Veterinary Sciences |
| spelling | doaj.art-cf17c3cf6d9b422f9962b9dc82e3b2d72023-12-03T12:23:41ZengMDPI AGVeterinary Sciences2306-73812022-06-019731810.3390/vetsci9070318Seronegative <i>Myasthenia Gravis</i> with Concomitant SARS-CoV-2 Infection in a DogMihai Musteata0Denis-Gabriel Borcea1Andreea Despa2Raluca Ștefănescu3Larisa Ivănescu4Luminița Diana Hrițcu5Radu Andrei Baisan6Radu Lăcătuș7Gheorghe Solcan8Neurology Service, Faculty of Veterinary Medicine, Ion Ionescu de la Brad Iași University of Life Sciences, 700489 Iași, RomaniaNeurology Service, Faculty of Veterinary Medicine, Ion Ionescu de la Brad Iași University of Life Sciences, 700489 Iași, RomaniaNeurology Service, Faculty of Veterinary Medicine, Ion Ionescu de la Brad Iași University of Life Sciences, 700489 Iași, RomaniaNeurology Service, Faculty of Veterinary Medicine, Ion Ionescu de la Brad Iași University of Life Sciences, 700489 Iași, RomaniaParasitology Service, Faculty of Veterinary Medicine, Ion Ionescu de la Brad Iași University of Life Sciences, 700489 Iași, RomaniaInternal Medicine Clinic, Faculty of Veterinary Medicine, Ion Ionescu de la Brad Iași University of Life Sciences, 700489 Iași, RomaniaRadiology Unit, Faculty of Veterinary Medicine, Ion Ionescu de la Brad Iași University of Life Sciences, 700489 Iași, RomaniaFaculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, 400372 Cluj-Napoca, RomaniaInternal Medicine Clinic, Faculty of Veterinary Medicine, Ion Ionescu de la Brad Iași University of Life Sciences, 700489 Iași, Romania<i>Myasthenia gravis</i> (MG) is a disorder of neuromuscular transmission affecting the neuromuscular junction. The majority of cases involve an autoimmune attack against AChR, but a limited number of patients are seronegative for AChR antibodies. Viral infection is incriminated as a trigger for MG occurrence, and in a limited number of reports, infection with SARS-CoV-2 was found to be associated with MG expression in humans. In this report, we describe case of seronegative generalized MG in a 2-year-old crossbred female dog associated with SARS-CoV-2 infection due to close exposure to an infected owner.https://www.mdpi.com/2306-7381/9/7/318seronegative <i>myasthenia gravis</i>dogcoronavirus |
| spellingShingle | Mihai Musteata Denis-Gabriel Borcea Andreea Despa Raluca Ștefănescu Larisa Ivănescu Luminița Diana Hrițcu Radu Andrei Baisan Radu Lăcătuș Gheorghe Solcan Seronegative <i>Myasthenia Gravis</i> with Concomitant SARS-CoV-2 Infection in a Dog Veterinary Sciences seronegative <i>myasthenia gravis</i> dog coronavirus |
| title | Seronegative <i>Myasthenia Gravis</i> with Concomitant SARS-CoV-2 Infection in a Dog |
| title_full | Seronegative <i>Myasthenia Gravis</i> with Concomitant SARS-CoV-2 Infection in a Dog |
| title_fullStr | Seronegative <i>Myasthenia Gravis</i> with Concomitant SARS-CoV-2 Infection in a Dog |
| title_full_unstemmed | Seronegative <i>Myasthenia Gravis</i> with Concomitant SARS-CoV-2 Infection in a Dog |
| title_short | Seronegative <i>Myasthenia Gravis</i> with Concomitant SARS-CoV-2 Infection in a Dog |
| title_sort | seronegative i myasthenia gravis i with concomitant sars cov 2 infection in a dog |
| topic | seronegative <i>myasthenia gravis</i> dog coronavirus |
| url | https://www.mdpi.com/2306-7381/9/7/318 |
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