Metabolism drives macrophage heterogeneity in the tumor microenvironment

Metabolism drives macrophage heterogeneity in the tumor microenvironment

Summary: Tumor-associated macrophages (TAMs) are a major cellular component in the tumor microenvironment (TME). However, the relationship between the phenotype and metabolic pattern of TAMs remains poorly understood. We performed single-cell transcriptome profiling on hepatic TAMs from mice bearing...

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Bibliographic Details
Main Authors: Shasha Li, Jiali Yu, Amanda Huber, Ilona Kryczek, Zhuwen Wang, Long Jiang, Xiong Li, Wan Du, Gaopeng Li, Shuang Wei, Linda Vatan, Wojciech Szeliga, Arul M. Chinnaiyan, Michael D. Green, Marcin Cieslik, Weiping Zou
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Cell Reports
Subjects:
CP: Cancer
CP: Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722003576

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