The Role of Magnetic Resonance Imaging in the Differential Diagnosis of Giant Rectal and Perirectal Masses
Introduction:Our purpose was to depict some specific qualitative and quantitative magnetic resonance imaging (MRI) and diffusion weighted imaging (DWI) findings in differential diagnosis of huge tumors of rectum and perirectal region.Methods:A total of 81 patients who had ≥5 cm huge tumors of rectum...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2019-09-01
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| Series: | İstanbul Medical Journal |
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http://imj.galenos.com.tr/archives/archive-detail/article-preview/the-role-of-magnetic-resonance-maging-in-the-diffe/30573
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| _version_ | 1797909861464276992 |
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| author | Fatma Kulalı Özgül Düzgün |
| author_facet | Fatma Kulalı Özgül Düzgün |
| author_sort | Fatma Kulalı |
| collection | DOAJ |
| description | Introduction:Our purpose was to depict some specific qualitative and quantitative magnetic resonance imaging (MRI) and diffusion weighted imaging (DWI) findings in differential diagnosis of huge tumors of rectum and perirectal region.Methods:A total of 81 patients who had ≥5 cm huge tumors of rectum and perirectal region [36 (44%) women and 45 (56%) men] with a mean age of 54±15 (standard deviation) were enrolled in this retrospective study. Pre-operative MRI with DWI examinations of patients were reviewed by an experienced radiologist. Qualitative (signal intensity, contrast enhancement pattern, the existence of lymphadenopathy and metastasis) and quantitative imaging findings were statistically analyzed according to histopathological results.Results:Of 81 huge tumors of rectum and perirectal region, 60 were malignant and 21 were benign. Among (n=60) malignant tumors, there were 48 rectal adenocancers, two prostate adenocancers, three leiomyosarcomas, three ovarian cancers and four rectal gastrointestinal stromal tumors (GISTs). All rectal GISTs (n=4) showed peripheral heterogeneous arterial enhancement and had hypointense peripheral components whereas central components were more heterogeneous and iso-/hyper-intense on T2-weighted sequences. Most of rectal adenocancers (41/48, 85%) showed significant enhancement. Lymphadenopathy, invasion and far metastasis were only observed in malignant tumors. Mean “apparent diffusion coefficient” (ADC) ratios of malignant tumors (0.56±0.10) were significantly lower than those of benign tumors (0.95±0.21) (p<0.05).Conclusion:Specific MRI findings combining with ADC ratio estimation can be helpful for differential diagnosis of bulky rectal and perirectal tumor, and appropriate management of patient. |
| first_indexed | 2024-04-10T11:14:58Z |
| format | Article |
| id | doaj.art-cf19f061b19d4eb884fb9368cf708cab |
| institution | Directory Open Access Journal |
| issn | 2619-9793 2148-094X |
| language | English |
| last_indexed | 2024-04-10T11:14:58Z |
| publishDate | 2019-09-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | İstanbul Medical Journal |
| spelling | doaj.art-cf19f061b19d4eb884fb9368cf708cab2023-02-15T16:18:53ZengGalenos Yayineviİstanbul Medical Journal2619-97932148-094X2019-09-0120541842310.4274/imj.galenos.2019.7847613049054The Role of Magnetic Resonance Imaging in the Differential Diagnosis of Giant Rectal and Perirectal MassesFatma Kulalı0Özgül Düzgün1 University of Health Sciences Ümraniye Training and Research Hospital, Clinic of Radiology, İstanbul, Turkey niversity of Health Sciences Ümraniye Training and Research Hospital, Clinic of General Surgery, İstanbul, Turkey Introduction:Our purpose was to depict some specific qualitative and quantitative magnetic resonance imaging (MRI) and diffusion weighted imaging (DWI) findings in differential diagnosis of huge tumors of rectum and perirectal region.Methods:A total of 81 patients who had ≥5 cm huge tumors of rectum and perirectal region [36 (44%) women and 45 (56%) men] with a mean age of 54±15 (standard deviation) were enrolled in this retrospective study. Pre-operative MRI with DWI examinations of patients were reviewed by an experienced radiologist. Qualitative (signal intensity, contrast enhancement pattern, the existence of lymphadenopathy and metastasis) and quantitative imaging findings were statistically analyzed according to histopathological results.Results:Of 81 huge tumors of rectum and perirectal region, 60 were malignant and 21 were benign. Among (n=60) malignant tumors, there were 48 rectal adenocancers, two prostate adenocancers, three leiomyosarcomas, three ovarian cancers and four rectal gastrointestinal stromal tumors (GISTs). All rectal GISTs (n=4) showed peripheral heterogeneous arterial enhancement and had hypointense peripheral components whereas central components were more heterogeneous and iso-/hyper-intense on T2-weighted sequences. Most of rectal adenocancers (41/48, 85%) showed significant enhancement. Lymphadenopathy, invasion and far metastasis were only observed in malignant tumors. Mean “apparent diffusion coefficient” (ADC) ratios of malignant tumors (0.56±0.10) were significantly lower than those of benign tumors (0.95±0.21) (p<0.05).Conclusion:Specific MRI findings combining with ADC ratio estimation can be helpful for differential diagnosis of bulky rectal and perirectal tumor, and appropriate management of patient. http://imj.galenos.com.tr/archives/archive-detail/article-preview/the-role-of-magnetic-resonance-maging-in-the-diffe/30573 gastrointestinal stromal tumormagnetic resonance imagingrectal cancerdiffusion weighted imaging |
| spellingShingle | Fatma Kulalı Özgül Düzgün The Role of Magnetic Resonance Imaging in the Differential Diagnosis of Giant Rectal and Perirectal Masses İstanbul Medical Journal gastrointestinal stromal tumor magnetic resonance imaging rectal cancer diffusion weighted imaging |
| title | The Role of Magnetic Resonance Imaging in the Differential Diagnosis of Giant Rectal and Perirectal Masses |
| title_full | The Role of Magnetic Resonance Imaging in the Differential Diagnosis of Giant Rectal and Perirectal Masses |
| title_fullStr | The Role of Magnetic Resonance Imaging in the Differential Diagnosis of Giant Rectal and Perirectal Masses |
| title_full_unstemmed | The Role of Magnetic Resonance Imaging in the Differential Diagnosis of Giant Rectal and Perirectal Masses |
| title_short | The Role of Magnetic Resonance Imaging in the Differential Diagnosis of Giant Rectal and Perirectal Masses |
| title_sort | role of magnetic resonance imaging in the differential diagnosis of giant rectal and perirectal masses |
| topic | gastrointestinal stromal tumor magnetic resonance imaging rectal cancer diffusion weighted imaging |
| url |
http://imj.galenos.com.tr/archives/archive-detail/article-preview/the-role-of-magnetic-resonance-maging-in-the-diffe/30573
|
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