Does epigenetics play a role in human asthma?
Asthma and other allergic diseases are among the most prevalent chronic non-communicable diseases of childhood. According to the World Health Organization, asthma affects >7.0 million children under 18 in the United States, with an economic burden that is estimated to exceed that of tuberculosis...
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| Format: | Article |
| Language: | English |
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Elsevier
2016-04-01
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| Series: | Allergology International |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1323893015002130 |
| _version_ | 1818250762381164544 |
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| author | Donata Vercelli |
| author_facet | Donata Vercelli |
| author_sort | Donata Vercelli |
| collection | DOAJ |
| description | Asthma and other allergic diseases are among the most prevalent chronic non-communicable diseases of childhood. According to the World Health Organization, asthma affects >7.0 million children under 18 in the United States, with an economic burden that is estimated to exceed that of tuberculosis and HIV/AIDS combined. Despite much research, the natural history of asthma and its pathogenesis are still in many ways elusive. This review discusses our current understanding of the role epigenetic processes play in asthma pathogenesis, focusing on genome-wide, population-based studies. |
| first_indexed | 2024-12-12T15:57:32Z |
| format | Article |
| id | doaj.art-cf1bd6cc2b584ead9093ff3081e4404a |
| institution | Directory Open Access Journal |
| issn | 1323-8930 |
| language | English |
| last_indexed | 2024-12-12T15:57:32Z |
| publishDate | 2016-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Allergology International |
| spelling | doaj.art-cf1bd6cc2b584ead9093ff3081e4404a2022-12-22T00:19:27ZengElsevierAllergology International1323-89302016-04-0165212312610.1016/j.alit.2015.12.001Does epigenetics play a role in human asthma?Donata VercelliAsthma and other allergic diseases are among the most prevalent chronic non-communicable diseases of childhood. According to the World Health Organization, asthma affects >7.0 million children under 18 in the United States, with an economic burden that is estimated to exceed that of tuberculosis and HIV/AIDS combined. Despite much research, the natural history of asthma and its pathogenesis are still in many ways elusive. This review discusses our current understanding of the role epigenetic processes play in asthma pathogenesis, focusing on genome-wide, population-based studies.http://www.sciencedirect.com/science/article/pii/S1323893015002130AllergyBirth cohortChildhood asthmaDNA methylationEpigenetics |
| spellingShingle | Donata Vercelli Does epigenetics play a role in human asthma? Allergology International Allergy Birth cohort Childhood asthma DNA methylation Epigenetics |
| title | Does epigenetics play a role in human asthma? |
| title_full | Does epigenetics play a role in human asthma? |
| title_fullStr | Does epigenetics play a role in human asthma? |
| title_full_unstemmed | Does epigenetics play a role in human asthma? |
| title_short | Does epigenetics play a role in human asthma? |
| title_sort | does epigenetics play a role in human asthma |
| topic | Allergy Birth cohort Childhood asthma DNA methylation Epigenetics |
| url | http://www.sciencedirect.com/science/article/pii/S1323893015002130 |
| work_keys_str_mv | AT donatavercelli doesepigeneticsplayaroleinhumanasthma |