Biotin IgM antibodies in human blood: a previously unknown factor eliciting false results in biotinylation-based immunoassays.
Biotin is an essential vitamin that binds streptavidin or avidin with high affinity and specificity. As biotin is a small molecule that can be linked to proteins without affecting their biological activity, biotinylation is applied widely in biochemical assays. In our laboratory, IgM enzyme immuno a...
Päätekijät: | , , , , , , , |
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Aineistotyyppi: | Artikkeli |
Kieli: | English |
Julkaistu: |
Public Library of Science (PLoS)
2012-01-01
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Sarja: | PLoS ONE |
Linkit: | http://europepmc.org/articles/PMC3411747?pdf=render |