Using Genetic Code Expansion for Protein Biochemical Studies

Using Genetic Code Expansion for Protein Biochemical Studies

Protein identification has gone beyond simply using protein/peptide tags and labeling canonical amino acids. Genetic code expansion has allowed residue- or site-specific incorporation of non-canonical amino acids into proteins. By taking advantage of the unique properties of non-canonical amino acid...

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Bibliographic Details
Main Authors: Christina Z. Chung, Kazuaki Amikura, Dieter Söll
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
genetic code expansion
non-canonical amino acids
protein labeling
protein purification
protein–protein interactions
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.598577/full

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