Efficacy of an experimental E. coli inactivated vaccine in turkey poults
E. coli infections are responsible for great economic losses in the poultry industry worldwide, bringing serious threat to the turkey industry. The present investigation aimed to prepare a potent vaccine from E. coli serogroups O1 and O78 to aid in control of colibacillosis in turkey. One hundred co...
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| Format: | Article |
| Language: | English |
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Egyptian Society for Animal Management
2016-10-01
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| Series: | Journal of Applied Veterinary Sciences |
| Subjects: | |
| Online Access: | https://javs.journals.ekb.eg/article_61820.html |
| _version_ | 1818572952798494720 |
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| author | Gina M. Mohammed Shell W.S. Sayed M.L. Ibrahim H.M. Hanan M.H. Ghada M. El-Sadek |
| author_facet | Gina M. Mohammed Shell W.S. Sayed M.L. Ibrahim H.M. Hanan M.H. Ghada M. El-Sadek |
| author_sort | Gina M. Mohammed |
| collection | DOAJ |
| description | E. coli infections are responsible for great economic losses in the poultry industry worldwide, bringing serious threat to the turkey industry. The present investigation aimed to prepare a potent vaccine from E. coli serogroups O1 and O78 to aid in control of colibacillosis in turkey. One hundred commercial 14 days-old turkey poults were used and divided into three groups; first group was vaccinated twice with 3 weeks interval by prepared inactivated E.coli vaccine adjuvanted with aluminum hydroxide gel, second group was vaccinated twice with 3 weeks interval by prepared inactivated E.coli vaccine adjuvanted with montanide ISA70, third group was left as unvaccinated control one. The immune response was measured by MAT (Microagglutination test), ELISA and challenge test. It was found that the protection rate for inactivated vaccine with aluminum hydroxide gel and E.coli inactivated vaccine with montanide ISA70 were 80% and 85% respectively although it was 30% among the unvaccinated group. |
| first_indexed | 2024-12-15T00:04:32Z |
| format | Article |
| id | doaj.art-cf20967745ed4146adea24f095da1250 |
| institution | Directory Open Access Journal |
| issn | 1687-4072 2090-3308 |
| language | English |
| last_indexed | 2024-12-15T00:04:32Z |
| publishDate | 2016-10-01 |
| publisher | Egyptian Society for Animal Management |
| record_format | Article |
| series | Journal of Applied Veterinary Sciences |
| spelling | doaj.art-cf20967745ed4146adea24f095da12502022-12-21T22:42:47ZengEgyptian Society for Animal ManagementJournal of Applied Veterinary Sciences1687-40722090-33082016-10-0111710.21608/javs.2016.61820Efficacy of an experimental E. coli inactivated vaccine in turkey poultsGina M. Mohammed0Shell W.S.1Sayed M.L. 2Ibrahim H.M. 3Hanan M.H. 4Ghada M. El-Sadek5Central Laboratory for Evaluation Veterinary Biologics, Abbasia, Cairo, Egypt.Central Laboratory for Evaluation Veterinary Biologics, Abbasia, Cairo, Egypt.Central Laboratory for Evaluation Veterinary Biologics, Abbasia, Cairo, Egypt.Veterinary Serum and Vaccine Research Institute, Abbasia, Cairo, Egypt.Central Laboratory for Evaluation Veterinary Biologics, Abbasia, Cairo, Egypt.Central Laboratory for Evaluation Veterinary Biologics, Abbasia, Cairo, Egypt.E. coli infections are responsible for great economic losses in the poultry industry worldwide, bringing serious threat to the turkey industry. The present investigation aimed to prepare a potent vaccine from E. coli serogroups O1 and O78 to aid in control of colibacillosis in turkey. One hundred commercial 14 days-old turkey poults were used and divided into three groups; first group was vaccinated twice with 3 weeks interval by prepared inactivated E.coli vaccine adjuvanted with aluminum hydroxide gel, second group was vaccinated twice with 3 weeks interval by prepared inactivated E.coli vaccine adjuvanted with montanide ISA70, third group was left as unvaccinated control one. The immune response was measured by MAT (Microagglutination test), ELISA and challenge test. It was found that the protection rate for inactivated vaccine with aluminum hydroxide gel and E.coli inactivated vaccine with montanide ISA70 were 80% and 85% respectively although it was 30% among the unvaccinated group.https://javs.journals.ekb.eg/article_61820.htmle. colielisainactivated vaccinematcentral laboratory for evaluation veterinary biologicsabbasiacairo |
| spellingShingle | Gina M. Mohammed Shell W.S. Sayed M.L. Ibrahim H.M. Hanan M.H. Ghada M. El-Sadek Efficacy of an experimental E. coli inactivated vaccine in turkey poults Journal of Applied Veterinary Sciences e. coli elisa inactivated vaccine mat central laboratory for evaluation veterinary biologics abbasia cairo |
| title | Efficacy of an experimental E. coli inactivated vaccine in turkey poults |
| title_full | Efficacy of an experimental E. coli inactivated vaccine in turkey poults |
| title_fullStr | Efficacy of an experimental E. coli inactivated vaccine in turkey poults |
| title_full_unstemmed | Efficacy of an experimental E. coli inactivated vaccine in turkey poults |
| title_short | Efficacy of an experimental E. coli inactivated vaccine in turkey poults |
| title_sort | efficacy of an experimental e coli inactivated vaccine in turkey poults |
| topic | e. coli elisa inactivated vaccine mat central laboratory for evaluation veterinary biologics abbasia cairo |
| url | https://javs.journals.ekb.eg/article_61820.html |
| work_keys_str_mv | AT ginammohammed efficacyofanexperimentalecoliinactivatedvaccineinturkeypoults AT shellws efficacyofanexperimentalecoliinactivatedvaccineinturkeypoults AT sayedml efficacyofanexperimentalecoliinactivatedvaccineinturkeypoults AT ibrahimhm efficacyofanexperimentalecoliinactivatedvaccineinturkeypoults AT hananmh efficacyofanexperimentalecoliinactivatedvaccineinturkeypoults AT ghadamelsadek efficacyofanexperimentalecoliinactivatedvaccineinturkeypoults |