Burden of malaria in pregnancy in Jharkhand State, India
<p>Abstract</p> <p>Background</p> <p>Past studies in India included only symptomatic pregnant women and thus may have overestimated the proportion of women with malaria. Given the large population at risk, a cross sectional study was conducted in order to better define...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2009-09-01
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| Series: | Malaria Journal |
| Online Access: | http://www.malariajournal.com/content/8/1/210 |
| _version_ | 1818261786915241984 |
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| author | Brooks Mohamad I Gupta Priti Udhayakumar Venkatachalam Desai Meghna Tuchman Jordan Yeboah-Antwi Kojo Wylie Blair J Singh Mrigendra P Hamer Davidson H Shukla Manmohan M Awasthy Kiran Sabin Lora MacLeod William B Dash Aditya P Singh Neeru |
| author_facet | Brooks Mohamad I Gupta Priti Udhayakumar Venkatachalam Desai Meghna Tuchman Jordan Yeboah-Antwi Kojo Wylie Blair J Singh Mrigendra P Hamer Davidson H Shukla Manmohan M Awasthy Kiran Sabin Lora MacLeod William B Dash Aditya P Singh Neeru |
| author_sort | Brooks Mohamad I |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Past studies in India included only symptomatic pregnant women and thus may have overestimated the proportion of women with malaria. Given the large population at risk, a cross sectional study was conducted in order to better define the burden of malaria in pregnancy in Jharkhand, a malaria-endemic state in central-east India.</p> <p>Methods</p> <p>Cross-sectional surveys at antenatal clinics and delivery units were performed over a 12-month period at two district hospitals in urban and semi-urban areas, and a rural mission hospital. Malaria was diagnosed by Giemsa-stained blood smear and/or rapid diagnostic test using peripheral or placental blood.</p> <p>Results</p> <p>2,386 pregnant women were enrolled at the antenatal clinics and 718 at the delivery units. 1.8% (43/2382) of the antenatal clinic cohort had a positive diagnostic test for malaria (53.5% <it>Plasmodium falciparum</it>, 37.2% <it>Plasmodium vivax</it>, and 9.3% mixed infections). Peripheral parasitaemia was more common in pregnant women attending antenatal clinics in rural sites (adjusted relative risk [aRR] 4.31, 95%CI 1.84-10.11) and in those who were younger than 20 years (aRR 2.68, 95%CI 1.03-6.98). Among delivery unit participants, 1.7% (12/717) had peripheral parasitaemia and 2.4% (17/712) had placental parasitaemia. Women attending delivery units were more likely to be parasitaemic if they were in their first or second pregnancy (aRR 3.17, 95%CI 1.32-7.61), had fever in the last week (aRR 5.34, 95%CI 2.89-9.90), or had rural residence (aRR 3.10, 95%CI 1.66-5.79). Malaria control measures including indoor residual spraying (IRS) and untreated bed nets were common, whereas insecticide-treated bed nets (ITN) and malaria chemoprophylaxis were rarely used.</p> <p>Conclusion</p> <p>The prevalence of malaria among pregnant women was relatively low. However, given the large at-risk population in this malaria-endemic region of India, there is a need to enhance ITN availability and use for prevention of malaria in pregnancy, and to improve case management of symptomatic pregnant women.</p> |
| first_indexed | 2024-12-12T18:52:46Z |
| format | Article |
| id | doaj.art-cf22701cc0dc496ea1e92c1cccbfff6a |
| institution | Directory Open Access Journal |
| issn | 1475-2875 |
| language | English |
| last_indexed | 2024-12-12T18:52:46Z |
| publishDate | 2009-09-01 |
| publisher | BMC |
| record_format | Article |
| series | Malaria Journal |
| spelling | doaj.art-cf22701cc0dc496ea1e92c1cccbfff6a2022-12-22T00:15:20ZengBMCMalaria Journal1475-28752009-09-018121010.1186/1475-2875-8-210Burden of malaria in pregnancy in Jharkhand State, IndiaBrooks Mohamad IGupta PritiUdhayakumar VenkatachalamDesai MeghnaTuchman JordanYeboah-Antwi KojoWylie Blair JSingh Mrigendra PHamer Davidson HShukla Manmohan MAwasthy KiranSabin LoraMacLeod William BDash Aditya PSingh Neeru<p>Abstract</p> <p>Background</p> <p>Past studies in India included only symptomatic pregnant women and thus may have overestimated the proportion of women with malaria. Given the large population at risk, a cross sectional study was conducted in order to better define the burden of malaria in pregnancy in Jharkhand, a malaria-endemic state in central-east India.</p> <p>Methods</p> <p>Cross-sectional surveys at antenatal clinics and delivery units were performed over a 12-month period at two district hospitals in urban and semi-urban areas, and a rural mission hospital. Malaria was diagnosed by Giemsa-stained blood smear and/or rapid diagnostic test using peripheral or placental blood.</p> <p>Results</p> <p>2,386 pregnant women were enrolled at the antenatal clinics and 718 at the delivery units. 1.8% (43/2382) of the antenatal clinic cohort had a positive diagnostic test for malaria (53.5% <it>Plasmodium falciparum</it>, 37.2% <it>Plasmodium vivax</it>, and 9.3% mixed infections). Peripheral parasitaemia was more common in pregnant women attending antenatal clinics in rural sites (adjusted relative risk [aRR] 4.31, 95%CI 1.84-10.11) and in those who were younger than 20 years (aRR 2.68, 95%CI 1.03-6.98). Among delivery unit participants, 1.7% (12/717) had peripheral parasitaemia and 2.4% (17/712) had placental parasitaemia. Women attending delivery units were more likely to be parasitaemic if they were in their first or second pregnancy (aRR 3.17, 95%CI 1.32-7.61), had fever in the last week (aRR 5.34, 95%CI 2.89-9.90), or had rural residence (aRR 3.10, 95%CI 1.66-5.79). Malaria control measures including indoor residual spraying (IRS) and untreated bed nets were common, whereas insecticide-treated bed nets (ITN) and malaria chemoprophylaxis were rarely used.</p> <p>Conclusion</p> <p>The prevalence of malaria among pregnant women was relatively low. However, given the large at-risk population in this malaria-endemic region of India, there is a need to enhance ITN availability and use for prevention of malaria in pregnancy, and to improve case management of symptomatic pregnant women.</p>http://www.malariajournal.com/content/8/1/210 |
| spellingShingle | Brooks Mohamad I Gupta Priti Udhayakumar Venkatachalam Desai Meghna Tuchman Jordan Yeboah-Antwi Kojo Wylie Blair J Singh Mrigendra P Hamer Davidson H Shukla Manmohan M Awasthy Kiran Sabin Lora MacLeod William B Dash Aditya P Singh Neeru Burden of malaria in pregnancy in Jharkhand State, India Malaria Journal |
| title | Burden of malaria in pregnancy in Jharkhand State, India |
| title_full | Burden of malaria in pregnancy in Jharkhand State, India |
| title_fullStr | Burden of malaria in pregnancy in Jharkhand State, India |
| title_full_unstemmed | Burden of malaria in pregnancy in Jharkhand State, India |
| title_short | Burden of malaria in pregnancy in Jharkhand State, India |
| title_sort | burden of malaria in pregnancy in jharkhand state india |
| url | http://www.malariajournal.com/content/8/1/210 |
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