COVID‐19 infection and pain in adolescents with sickle cell disease: A case series

Abstract Adolescents with sickle cell disease (SCD) have been shown to have pain‐related sequelae following COVID‐19 infection. In this case series, we discuss five adolescents with SCD and SARS‐CoV‐2 infection who subsequently developed complex pain circumstances manifested as: (1) increased freque...

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Main Authors: Heidi M. Heyman, Nicole M. Alberts, Matthew Rees, Latika Puri, Michael J. Frett, Doralina L. Anghelescu
Format: Article
Language:English
Published: Wiley 2022-11-01
Series:eJHaem
Subjects:
Online Access:https://doi.org/10.1002/jha2.587
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author Heidi M. Heyman
Nicole M. Alberts
Matthew Rees
Latika Puri
Michael J. Frett
Doralina L. Anghelescu
author_facet Heidi M. Heyman
Nicole M. Alberts
Matthew Rees
Latika Puri
Michael J. Frett
Doralina L. Anghelescu
author_sort Heidi M. Heyman
collection DOAJ
description Abstract Adolescents with sickle cell disease (SCD) have been shown to have pain‐related sequelae following COVID‐19 infection. In this case series, we discuss five adolescents with SCD and SARS‐CoV‐2 infection who subsequently developed complex pain circumstances manifested as: (1) increased frequency of acute care visits or admissions for pain; (2) new onset chronic pain; (3) new onset neuropathic pain; (4) escalation in the complexity of pharmacologic therapies; (5) increased use of nonpharmacologic interventions. While more research is needed to fully understand the implications of COVID‐19 infection on pain in adolescents with SCD, these cases suggest the presence of a complex relationship.
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spelling doaj.art-cf2526be8e59473791d2dd79e57a51ed2023-10-03T16:50:47ZengWileyeJHaem2688-61462022-11-01341310131510.1002/jha2.587COVID‐19 infection and pain in adolescents with sickle cell disease: A case seriesHeidi M. Heyman0Nicole M. Alberts1Matthew Rees2Latika Puri3Michael J. Frett4Doralina L. Anghelescu5Department of Pediatric Medicine Division of Anesthesiology St. Jude Children's Research Hospital Memphis Tennessee USADepartment of Psychology Concordia University Montréal Quebec CanadaDepartment of Oncology St. Jude Children's Research Hospital Memphis Tennessee USADepartment of Hematology Loma Linda University Loma Linda California USADepartment of Pediatric Medicine Division of Anesthesiology St. Jude Children's Research Hospital Memphis Tennessee USADepartment of Pediatric Medicine Division of Anesthesiology St. Jude Children's Research Hospital Memphis Tennessee USAAbstract Adolescents with sickle cell disease (SCD) have been shown to have pain‐related sequelae following COVID‐19 infection. In this case series, we discuss five adolescents with SCD and SARS‐CoV‐2 infection who subsequently developed complex pain circumstances manifested as: (1) increased frequency of acute care visits or admissions for pain; (2) new onset chronic pain; (3) new onset neuropathic pain; (4) escalation in the complexity of pharmacologic therapies; (5) increased use of nonpharmacologic interventions. While more research is needed to fully understand the implications of COVID‐19 infection on pain in adolescents with SCD, these cases suggest the presence of a complex relationship.https://doi.org/10.1002/jha2.587anemiachronic painCOVID‐19neuropathic painsickle cell diseasevaso‐occlusive crisis
spellingShingle Heidi M. Heyman
Nicole M. Alberts
Matthew Rees
Latika Puri
Michael J. Frett
Doralina L. Anghelescu
COVID‐19 infection and pain in adolescents with sickle cell disease: A case series
eJHaem
anemia
chronic pain
COVID‐19
neuropathic pain
sickle cell disease
vaso‐occlusive crisis
title COVID‐19 infection and pain in adolescents with sickle cell disease: A case series
title_full COVID‐19 infection and pain in adolescents with sickle cell disease: A case series
title_fullStr COVID‐19 infection and pain in adolescents with sickle cell disease: A case series
title_full_unstemmed COVID‐19 infection and pain in adolescents with sickle cell disease: A case series
title_short COVID‐19 infection and pain in adolescents with sickle cell disease: A case series
title_sort covid 19 infection and pain in adolescents with sickle cell disease a case series
topic anemia
chronic pain
COVID‐19
neuropathic pain
sickle cell disease
vaso‐occlusive crisis
url https://doi.org/10.1002/jha2.587
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