Estimating biological reference intervals for cell blood counts in a dog population

Background: The results from automated equipment and peripheral blood smears allow correlating clinical data with cellular blood counts (CBC), generating information on pathologies of hematological and non-hematological origin in dogs. Objective: To describe qualitative and quantitative magnitudes o...

Full description

Bibliographic Details
Main Authors: Valentina Ochoa-Ruíz, Víctor D. Velasco-Pérez, Margarita Patiño, Jhonatan S. Restrepo-León, Jannet Zapata-Bailarín, Nathalia M. Correa-Valencia, Patricia E. Jaramillo-Arbeláez
Format: Article
Language:English
Published: Universidad de Antioquia 2020-09-01
Series:Revista Colombiana de Ciencias Pecuarias
Subjects:
Online Access:https://revistas.udea.edu.co/index.php/rccp/article/view/343952
_version_ 1827584424702640128
author Valentina Ochoa-Ruíz
Víctor D. Velasco-Pérez
Margarita Patiño
Jhonatan S. Restrepo-León
Jannet Zapata-Bailarín
Nathalia M. Correa-Valencia
Patricia E. Jaramillo-Arbeláez
author_facet Valentina Ochoa-Ruíz
Víctor D. Velasco-Pérez
Margarita Patiño
Jhonatan S. Restrepo-León
Jannet Zapata-Bailarín
Nathalia M. Correa-Valencia
Patricia E. Jaramillo-Arbeláez
author_sort Valentina Ochoa-Ruíz
collection DOAJ
description Background: The results from automated equipment and peripheral blood smears allow correlating clinical data with cellular blood counts (CBC), generating information on pathologies of hematological and non-hematological origin in dogs. Objective: To describe qualitative and quantitative magnitudes of CBC in healthy donor dogs of a blood- bank in Medellín (Colombia). Methods: A descriptive-prospective study was carried out from 146 records of CBC results from a blood-bank. The samples were processed by automated equipment, and trained personnel performed the observation of peripheral blood smears to collect qualitative information. Variables such as age, sex, breed, quantitative results, and observations of the peripheral blood smears were considered. For the definition of biological intervals (BIs), the mean and two standard deviations were used for the data with a normal distribution. Otherwise, the 2.5th and 97.5th percentiles were used. Results: The size, granularity, and cytoplasmic vacuoles in monocytes and polymorphonuclear eosinophils, as well as the presence of Barr chromatin and occasional circulating erythroblasts, were remarkable findings to the peripheral blood smear. With the standardization of data obtained from dogs of large and giant breeds, the present work provides BIs for some of the CBC data in the studied population. Conclusion: The findings of the present study allow approximations to the definition of alterations in blood cells and their counts, which can guide the veterinarian towards an early diagnosis in dogs.
first_indexed 2024-03-08T23:30:09Z
format Article
id doaj.art-cf27aa6f60fc42c99edecc8b73f16059
institution Directory Open Access Journal
issn 2256-2958
language English
last_indexed 2024-03-08T23:30:09Z
publishDate 2020-09-01
publisher Universidad de Antioquia
record_format Article
series Revista Colombiana de Ciencias Pecuarias
spelling doaj.art-cf27aa6f60fc42c99edecc8b73f160592023-12-14T15:28:47ZengUniversidad de AntioquiaRevista Colombiana de Ciencias Pecuarias2256-29582020-09-0134212614410.17533/udea.rccp.v34n2a0741365Estimating biological reference intervals for cell blood counts in a dog populationValentina Ochoa-Ruíz0Víctor D. Velasco-Pérez1Margarita Patiño2Jhonatan S. Restrepo-León3Jannet Zapata-Bailarín4Nathalia M. Correa-Valencia5Patricia E. Jaramillo-Arbeláez6University of AntioquiaUniversity of AntioquiaTestLab LaboratoryTestLab LaboratoryUniversity of AntioquiaUniversity of AntioquiaUniversity of AntioquiaBackground: The results from automated equipment and peripheral blood smears allow correlating clinical data with cellular blood counts (CBC), generating information on pathologies of hematological and non-hematological origin in dogs. Objective: To describe qualitative and quantitative magnitudes of CBC in healthy donor dogs of a blood- bank in Medellín (Colombia). Methods: A descriptive-prospective study was carried out from 146 records of CBC results from a blood-bank. The samples were processed by automated equipment, and trained personnel performed the observation of peripheral blood smears to collect qualitative information. Variables such as age, sex, breed, quantitative results, and observations of the peripheral blood smears were considered. For the definition of biological intervals (BIs), the mean and two standard deviations were used for the data with a normal distribution. Otherwise, the 2.5th and 97.5th percentiles were used. Results: The size, granularity, and cytoplasmic vacuoles in monocytes and polymorphonuclear eosinophils, as well as the presence of Barr chromatin and occasional circulating erythroblasts, were remarkable findings to the peripheral blood smear. With the standardization of data obtained from dogs of large and giant breeds, the present work provides BIs for some of the CBC data in the studied population. Conclusion: The findings of the present study allow approximations to the definition of alterations in blood cells and their counts, which can guide the veterinarian towards an early diagnosis in dogs.https://revistas.udea.edu.co/index.php/rccp/article/view/343952barr chromatinbiological intervalsbloodblood cellscaninescellular countchromatindogerythroblastserythrogramhematologyhemogram
spellingShingle Valentina Ochoa-Ruíz
Víctor D. Velasco-Pérez
Margarita Patiño
Jhonatan S. Restrepo-León
Jannet Zapata-Bailarín
Nathalia M. Correa-Valencia
Patricia E. Jaramillo-Arbeláez
Estimating biological reference intervals for cell blood counts in a dog population
Revista Colombiana de Ciencias Pecuarias
barr chromatin
biological intervals
blood
blood cells
canines
cellular count
chromatin
dog
erythroblasts
erythrogram
hematology
hemogram
title Estimating biological reference intervals for cell blood counts in a dog population
title_full Estimating biological reference intervals for cell blood counts in a dog population
title_fullStr Estimating biological reference intervals for cell blood counts in a dog population
title_full_unstemmed Estimating biological reference intervals for cell blood counts in a dog population
title_short Estimating biological reference intervals for cell blood counts in a dog population
title_sort estimating biological reference intervals for cell blood counts in a dog population
topic barr chromatin
biological intervals
blood
blood cells
canines
cellular count
chromatin
dog
erythroblasts
erythrogram
hematology
hemogram
url https://revistas.udea.edu.co/index.php/rccp/article/view/343952
work_keys_str_mv AT valentinaochoaruiz estimatingbiologicalreferenceintervalsforcellbloodcountsinadogpopulation
AT victordvelascoperez estimatingbiologicalreferenceintervalsforcellbloodcountsinadogpopulation
AT margaritapatino estimatingbiologicalreferenceintervalsforcellbloodcountsinadogpopulation
AT jhonatansrestrepoleon estimatingbiologicalreferenceintervalsforcellbloodcountsinadogpopulation
AT jannetzapatabailarin estimatingbiologicalreferenceintervalsforcellbloodcountsinadogpopulation
AT nathaliamcorreavalencia estimatingbiologicalreferenceintervalsforcellbloodcountsinadogpopulation
AT patriciaejaramilloarbelaez estimatingbiologicalreferenceintervalsforcellbloodcountsinadogpopulation