Endothelial nitric oxide synthase (eNOS)-NO signaling axis functions to promote the growth of prostate cancer stem-like cells

Endothelial nitric oxide synthase (eNOS)-NO signaling axis functions to promote the growth of prostate cancer stem-like cells

Abstract Background Accumulating evidence supports that prostate cancer stem-like cells (PCSCs) play significant roles in therapy resistance and metastasis of prostate cancer. Many studies also show that nitric oxide (NO) synthesized by NO synthases can function to promote tumor progression. However...

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Bibliographic Details
Main Authors: Weijie Gao, Yuliang Wang, Shan Yu, Zhu Wang, Taiyang Ma, Andrew Man-Lok Chan, Peter Ka-Fung Chiu, Chi-Fai Ng, Dinglan Wu, Franky Leung Chan
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Stem Cell Research & Therapy
Subjects:
Prostate cancer
Castration resistance
Prostate cancer stem-like cells
ERRα
ERG
eNOS
Online Access:https://doi.org/10.1186/s13287-022-02864-6

Internet

https://doi.org/10.1186/s13287-022-02864-6

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