Long non-coding RNA KCNQ1OT1 promotes cell viability and migration as well as inhibiting degradation of CHON-001 cells by regulating miR-126-5p/TRPS1 axis

Abstract Background Osteoarthritis (OA) is defined as a degenerative disease. Pivotal roles of long non-coding RNA (lncRNAs) in OA are widely elucidated. Herein, we intend to explore the function and molecular mechanism of lncRNA KCNQ1OT1 in CHON-001 cells. Methods Relative expression of KCNQ1OT1, m...

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Bibliographic Details
Main Authors: Binfeng Wang, Xiangwei Liu
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Advances in Rheumatology
Subjects:
Online Access:https://doi.org/10.1186/s42358-021-00187-3