Selenium in the Environment, Metabolism and Involvement in Body Functions
Selenium (Se34 79) is a metalloid which is close to sulfur (S) in terms of properties. The Se concentration in soil varies with type, texture and organic matter content of the soil and with rainfall. Its assimilation by plants is influenced by the physico-chemical properties of the soil (redox statu...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2013-03-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1420-3049/18/3/3292 |
| _version_ | 1811298510662795264 |
|---|---|
| author | Isabelle Dufrasne Louis Istasse Jean-Luc Hornick Youcef Mehdi |
| author_facet | Isabelle Dufrasne Louis Istasse Jean-Luc Hornick Youcef Mehdi |
| author_sort | Isabelle Dufrasne |
| collection | DOAJ |
| description | Selenium (Se34 79) is a metalloid which is close to sulfur (S) in terms of properties. The Se concentration in soil varies with type, texture and organic matter content of the soil and with rainfall. Its assimilation by plants is influenced by the physico-chemical properties of the soil (redox status, pH and microbial activity). The presence of Se in the atmosphere is linked to natural and anthropogenic activities. Selenoproteins, in which selenium is present as selenocysteine, present an important role in many body functions, such as antioxidant defense and the formation of thyroid hormones. Some selenoprotein metabolites play a role in cancer prevention. In the immune system, selenium stimulates antibody formation and activity of helper T cells, cytotoxic T cells and Natural Killer (NK) cells. The mechanisms of intestinal absorption of selenium differ depending on the chemical form of the element. Selenium is mainly absorbed in the duodenum and caecum by active transport through a sodium pump. The recommended daily intake of selenium varies from 60 μg/day for women, to 70 μg/day for men. In growing ruminants the requirements are estimated at 100 μg/kg dry matter and 200 μg/Kg for pregnant or lactating females. A deficiency can cause reproductive disorders in humans and animals. |
| first_indexed | 2024-04-13T06:21:15Z |
| format | Article |
| id | doaj.art-cf2d83d1d85548e58e0749218ccb5690 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-04-13T06:21:15Z |
| publishDate | 2013-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-cf2d83d1d85548e58e0749218ccb56902022-12-22T02:58:39ZengMDPI AGMolecules1420-30492013-03-011833292331110.3390/molecules18033292Selenium in the Environment, Metabolism and Involvement in Body FunctionsIsabelle DufrasneLouis IstasseJean-Luc HornickYoucef MehdiSelenium (Se34 79) is a metalloid which is close to sulfur (S) in terms of properties. The Se concentration in soil varies with type, texture and organic matter content of the soil and with rainfall. Its assimilation by plants is influenced by the physico-chemical properties of the soil (redox status, pH and microbial activity). The presence of Se in the atmosphere is linked to natural and anthropogenic activities. Selenoproteins, in which selenium is present as selenocysteine, present an important role in many body functions, such as antioxidant defense and the formation of thyroid hormones. Some selenoprotein metabolites play a role in cancer prevention. In the immune system, selenium stimulates antibody formation and activity of helper T cells, cytotoxic T cells and Natural Killer (NK) cells. The mechanisms of intestinal absorption of selenium differ depending on the chemical form of the element. Selenium is mainly absorbed in the duodenum and caecum by active transport through a sodium pump. The recommended daily intake of selenium varies from 60 μg/day for women, to 70 μg/day for men. In growing ruminants the requirements are estimated at 100 μg/kg dry matter and 200 μg/Kg for pregnant or lactating females. A deficiency can cause reproductive disorders in humans and animals.http://www.mdpi.com/1420-3049/18/3/3292seleniumselenoproteinenvironmentantioxidantselenium metabolismdeficiencyreproduction |
| spellingShingle | Isabelle Dufrasne Louis Istasse Jean-Luc Hornick Youcef Mehdi Selenium in the Environment, Metabolism and Involvement in Body Functions Molecules selenium selenoprotein environment antioxidant selenium metabolism deficiency reproduction |
| title | Selenium in the Environment, Metabolism and Involvement in Body Functions |
| title_full | Selenium in the Environment, Metabolism and Involvement in Body Functions |
| title_fullStr | Selenium in the Environment, Metabolism and Involvement in Body Functions |
| title_full_unstemmed | Selenium in the Environment, Metabolism and Involvement in Body Functions |
| title_short | Selenium in the Environment, Metabolism and Involvement in Body Functions |
| title_sort | selenium in the environment metabolism and involvement in body functions |
| topic | selenium selenoprotein environment antioxidant selenium metabolism deficiency reproduction |
| url | http://www.mdpi.com/1420-3049/18/3/3292 |
| work_keys_str_mv | AT isabelledufrasne seleniumintheenvironmentmetabolismandinvolvementinbodyfunctions AT louisistasse seleniumintheenvironmentmetabolismandinvolvementinbodyfunctions AT jeanluchornick seleniumintheenvironmentmetabolismandinvolvementinbodyfunctions AT youcefmehdi seleniumintheenvironmentmetabolismandinvolvementinbodyfunctions |