Can a Selective Serotonin Reuptake Inhibitor Act as a Glutamatergic Modulator?

Sertraline (Zoloft) and fluoxetine (Prozac) are selective serotonin reuptake inhibitors whose antidepressant mechanism of action is classically attributed to an elevation of the extracellular levels of serotonin in the synaptic cleft. However, the biological effects of these drugs seem to be more co...

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Bibliographic Details
Main Author: Marcos Emilio Frizzo, PhD
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:Current Therapeutic Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0011393X17300267