Generalized chorea due to delayed encephalopathy after acute carbon monoxide intoxication
Movement disorder due to delayed encephalopathy after carbon monoxide (CO) intoxication is uncommon. Generalized chorea, presenting as an initial symptom of delayed encephalopathy, is extremely rare. We describe a 60-year-old woman, who had completely recovered from acute CO poisoning, developed men...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2015-01-01
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| Series: | Annals of Indian Academy of Neurology |
| Subjects: | |
| Online Access: | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2015;volume=18;issue=1;spage=108;epage=110;aulast=Sung |
| _version_ | 1819151588824973312 |
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| author | Yueh-Feng Sung Ming-Hua Chen Giia-Sheun Peng Jiunn-Tay Lee |
| author_facet | Yueh-Feng Sung Ming-Hua Chen Giia-Sheun Peng Jiunn-Tay Lee |
| author_sort | Yueh-Feng Sung |
| collection | DOAJ |
| description | Movement disorder due to delayed encephalopathy after carbon monoxide (CO) intoxication is uncommon. Generalized chorea, presenting as an initial symptom of delayed encephalopathy, is extremely rare. We describe a 60-year-old woman, who had completely recovered from acute CO poisoning, developed mental and behavioral changes, urinary incontinence and generalized chorea 2 weeks thereafter. T2-weighted brain magnetic resonance imaging showed extensive hyperintensity of the bilateral periventricular and subcortical white matter and the globus pallidus. Brain single-photon emission computed tomography (SPECT) with technetium-99 ethylene cysteine dimer showed inhomogeneous perfusion in the cerebral cortex, with decreased uptake in bilateral frontal regions. Delayed encephalopathy after acute CO intoxication was diagnosed, and the symptoms gradually improved after hyperbaric oxygen therapy (HBOT). This case report demonstrates that generalized chorea may be one of the initial presenting symptoms of delayed encephalopathy after acute CO intoxication. We hypothesize that the generalized chorea in our patient may have been caused by the subcortical white matter lesions, which most likely interrupted the basal ganglia-thalamocortical circuits and that HBOT may be the treatment of choice for such patients. |
| first_indexed | 2024-12-22T14:35:47Z |
| format | Article |
| id | doaj.art-cf31c0eff3ed422dbc4249d734ca8b59 |
| institution | Directory Open Access Journal |
| issn | 0972-2327 1998-3549 |
| language | English |
| last_indexed | 2024-12-22T14:35:47Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Indian Academy of Neurology |
| spelling | doaj.art-cf31c0eff3ed422dbc4249d734ca8b592022-12-21T18:22:39ZengWolters Kluwer Medknow PublicationsAnnals of Indian Academy of Neurology0972-23271998-35492015-01-0118110811010.4103/0972-2327.144288Generalized chorea due to delayed encephalopathy after acute carbon monoxide intoxicationYueh-Feng SungMing-Hua ChenGiia-Sheun PengJiunn-Tay LeeMovement disorder due to delayed encephalopathy after carbon monoxide (CO) intoxication is uncommon. Generalized chorea, presenting as an initial symptom of delayed encephalopathy, is extremely rare. We describe a 60-year-old woman, who had completely recovered from acute CO poisoning, developed mental and behavioral changes, urinary incontinence and generalized chorea 2 weeks thereafter. T2-weighted brain magnetic resonance imaging showed extensive hyperintensity of the bilateral periventricular and subcortical white matter and the globus pallidus. Brain single-photon emission computed tomography (SPECT) with technetium-99 ethylene cysteine dimer showed inhomogeneous perfusion in the cerebral cortex, with decreased uptake in bilateral frontal regions. Delayed encephalopathy after acute CO intoxication was diagnosed, and the symptoms gradually improved after hyperbaric oxygen therapy (HBOT). This case report demonstrates that generalized chorea may be one of the initial presenting symptoms of delayed encephalopathy after acute CO intoxication. We hypothesize that the generalized chorea in our patient may have been caused by the subcortical white matter lesions, which most likely interrupted the basal ganglia-thalamocortical circuits and that HBOT may be the treatment of choice for such patients.http://www.annalsofian.org/article.asp?issn=0972-2327;year=2015;volume=18;issue=1;spage=108;epage=110;aulast=SungChoreacarbon monoxidehyperbaric oxygen therapymagnetic resonance imaging |
| spellingShingle | Yueh-Feng Sung Ming-Hua Chen Giia-Sheun Peng Jiunn-Tay Lee Generalized chorea due to delayed encephalopathy after acute carbon monoxide intoxication Annals of Indian Academy of Neurology Chorea carbon monoxide hyperbaric oxygen therapy magnetic resonance imaging |
| title | Generalized chorea due to delayed encephalopathy after acute carbon monoxide intoxication |
| title_full | Generalized chorea due to delayed encephalopathy after acute carbon monoxide intoxication |
| title_fullStr | Generalized chorea due to delayed encephalopathy after acute carbon monoxide intoxication |
| title_full_unstemmed | Generalized chorea due to delayed encephalopathy after acute carbon monoxide intoxication |
| title_short | Generalized chorea due to delayed encephalopathy after acute carbon monoxide intoxication |
| title_sort | generalized chorea due to delayed encephalopathy after acute carbon monoxide intoxication |
| topic | Chorea carbon monoxide hyperbaric oxygen therapy magnetic resonance imaging |
| url | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2015;volume=18;issue=1;spage=108;epage=110;aulast=Sung |
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