Novel HYDIN variants associated with male infertility in two Chinese families

Novel HYDIN variants associated with male infertility in two Chinese families

IntroductionInfertility is a major disease affecting human life and health, among which male factors account for about half. Asthenoteratozoospermia accounts for the majority of male infertility. High-throughput sequencing techniques have identified numerous variants in genes responsible for astheno...

Full description

Bibliographic Details
Main Authors:	Hui Yu, Xiao Shi, Zhongmei Shao, Hao Geng, Senzhao Guo, Kuokuo Li, Meng Gu, Chuan Xu, Yang Gao, Qing Tan, Zongliu Duan, Huan Wu, Rong Hua, Rui Guo, Zhaolian Wei, Ping Zhou, Yunxia Cao, Xiaojin He, Liang Li, Xiaoping Zhang, Mingrong Lv
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-01-01
Series:	Frontiers in Endocrinology
Subjects:	male infertility asthenoteratozoospermia whole-exome sequencing HYDIN acrosome ICSI
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2023.1118841/full

Similar Items

DNALI1 deficiency causes male infertility with severe asthenozoospermia in humans and mice by disrupting the assembly of the flagellar inner dynein arms and fibrous sheath
by: Huan Wu, et al.
Published: (2023-02-01)

Correction: Identification of deleterious variants in patients with male infertility due to idiopathic non-obstructive azoospermia
by: Dongdong Tang, et al.
Published: (2022-05-01)

Homozygous mutation in SLO3 leads to severe asthenoteratozoospermia due to acrosome hypoplasia and mitochondrial sheath malformations
by: Mingrong Lv, et al.
Published: (2022-01-01)

Editorial: Genetic factors in male infertility
by: Xiaojin He, et al.
Published: (2023-04-01)

Influencing factors and predictive model of live birth involving low-grade blastocyst frozen–thawed transfer: a retrospective study
by: Yuan Fang, et al.
Published: (2023-03-01)

Hsp90 is a potential risk factor for ovarian cancer prognosis: an evidence of a Chinese clinical center
by: Cancan Duan, et al.
Published: (2023-05-01)

Poor semen parameters are associated with abnormal methylation of imprinted genes in sperm DNA
by: Bing Song, et al.
Published: (2022-11-01)

Symptoms of an intrauterine hematoma associated with pregnancy complications: a systematic review.
by: Lan Xiang, et al.
Published: (2014-01-01)

Prioritizing de novo potential non-canonical splicing variants in neurodevelopmental disordersResearch in context
by: Kuokuo Li, et al.
Published: (2024-01-01)

Generation of an induced pluripotent stem cell line AMUFAHi002-A from polycystic ovary syndrome patient
by: Xiaohua Jiang, et al.
Published: (2022-08-01)

Mitochondrial DNA quantification correlates with the developmental potential of human euploid blastocysts but not with that of mosaic blastocysts
by: Wen Luo, et al.
Published: (2023-06-01)

Exploration of molecular features of PCOS with different androgen levels and immune-related prognostic biomarkers associated with implantation failure
by: Qinyu Gao, et al.
Published: (2022-08-01)

Spatial Data-Based Automatic and Quantitative Approach in Analyzing Maintenance Reachability
by: Jie Geng, et al.
Published: (2022-12-01)

An analysis of the applicability of integrating Confucian moral education ideas into the Civic Education of college students under the perspective of cultural communication
by: Yi Mingrong
Published: (2024-01-01)

HMGB1: a double-edged sword and therapeutic target in the female reproductive system
by: Yu Ren, et al.
Published: (2023-08-01)

Frozen embryo transfer in the menstrual cycle after moderate-severe ovarian hyperstimulation syndrome: a retrospective analysis
by: Yulu Yang, et al.
Published: (2022-12-01)

A New Urban Space Analysis Method Based on Space Syntax and Geographic Information System Using Multisource Data
by: Zhaolian Xing, et al.
Published: (2022-05-01)

Research on key technologies of multi-element monitoring data integration in intelligent mine
by: LI Guomin, et al.
Published: (2022-08-01)

Research on optimal coil configuration scheme of insulator relay WPT system
by: Wei Wang, et al.
Published: (2023-01-01)

Low-dose aspirin protects unexplained recurrent spontaneous abortion via downregulation of HMGB1 inflammation activation
by: Xiaofeng Xu, et al.
Published: (2022-11-01)

Mindfulness effects on postural control and attention
by: Cheong, Michelle Sara Mingrong
Published: (2014)

Effects of SARS-CoV-2 Vaccines on Sperm Quality: Systematic Review
by: Guanjian Li, et al.
Published: (2023-12-01)

Activation of MT1/MT2 to Protect Testes and Leydig Cells against Cisplatin-Induced Oxidative Stress through the SIRT1/Nrf2 Signaling Pathway
by: Junqiang Zhang, et al.
Published: (2022-05-01)

Correlation between heparanase gene polymorphism and susceptibility to endometrial cancer
by: Hanyu Cao, et al.
Published: (2020-10-01)

Effect of Flow on the Energy Conversion Characteristics of Multiphase Pumps Based on Energy Transport Theory
by: Manqi Tang, et al.
Published: (2023-12-01)

Study on Precipitation and Dissolution Mechanisms of Graphite in Hot Metal of Blast Furnace
by: Meng Xie, et al.
Published: (2022-09-01)

Study on Postfrac Softening Mechanism of Deep Marine Shale Reservoir in South Sichuan Basin
by: Zhou Xiaojin, et al.
Published: (2023-01-01)

The ability of critical care nurses to identify pressure injury and incontinence‐associated dermatitis: A multicentre cross‐sectional survey
by: Huan Liu, et al.
Published: (2023-03-01)

Guidelines on Cardiac Rehabilitation in Patients with Coronary Heart Disease: a Systematic Review
by: LIU Jingtao, SU He, QIN Xiaojin, LAN Yunxia, ZHANG Jinzhi
Published: (2023-07-01)

Fertility loss: negative effects of environmental toxicants on oogenesis
by: Xiaoxi Yao, et al.
Published: (2023-08-01)

Risk of cervical intraepithelial neoplasia grade 3 or more diagnoses for human papillomavirus16/18-positive women by cytology and co-infection status
by: Mengyin Ao, et al.
Published: (2023-10-01)

Controllability study of copper‐tin‐sulphide (Cu3SnS4) material based on the ratio adjustment of Cu to Sn elements
by: Mingrong Dong, et al.
Published: (2023-09-01)

Identification of TRPM2 as a Potential Therapeutic Target Associated with Immune Infiltration: A Comprehensive Pan-Cancer Analysis and Experimental Verification in Ovarian Cancer
by: Danxi Zheng, et al.
Published: (2023-07-01)

The survival outcome and complication of secondary cytoreductive surgery plus chemotherapy in recurrent ovarian cancer: a systematic review and meta-analysis
by: Ting Ding, et al.
Published: (2021-07-01)

Corrigendum: Editorial: MSC-derived exosomes in tissue regeneration
by: Xin-Ming Chen, et al.
Published: (2023-10-01)

Editorial: MSC-derived exosomes in tissue regeneration
by: Xin-Ming Chen, et al.
Published: (2023-09-01)

A High-Functional-Density Integrated Inertial Switch for Super-Quick Initiation and Reliable Self-Destruction of a Small-Caliber Projectile Fuze
by: Bo He, et al.
Published: (2023-07-01)

Aortic arch aneurysm presenting with Ortner's syndrome: A case report and literature review
by: Xiang Leyang, et al.
Published: (2023-03-01)

Organism type of infection is associated with prognosis in sepsis: an analysis from the MIMIC-IV database
by: Qiuping Guo, et al.
Published: (2023-06-01)

Transumbilical single-site laparoscopic parallel mattress suturing prevents bleeding and chronic pelvic pain in myomectomy: a retrospective cohort study of 124 cases with intramural fibroids
by: Xi Zeng, et al.
Published: (2022-05-01)