Suggestion of creatine as a new neurotransmitter by approaches ranging from chemical analysis and biochemistry to electrophysiology

The discovery of a new neurotransmitter, especially one in the central nervous system, is both important and difficult. We have been searching for new neurotransmitters for 12 y. We detected creatine (Cr) in synaptic vesicles (SVs) at a level lower than glutamate and gamma-aminobutyric acid but high...

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Bibliographic Details
Main Authors: Xiling Bian, Jiemin Zhu, Xiaobo Jia, Wenjun Liang, Sihan Yu, Zhiqiang Li, Wenxia Zhang, Yi Rao
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/89317