Interleukins: pathophysiological role in acute pancreatitis
Acute pancreatitis (AP) is a common inflammatory state characterized by a clinical course that can lead to serious local and extrapancreatic organ malfunction and failure. Interleukins (ILs) are biologically active glycoproteins primarily produced by macrophages and lymphocytes. According to the lit...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2024-01-01
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| Series: | Archives of Medical Science |
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| Online Access: | https://www.archivesofmedicalscience.com/Interleukins-pathophysiological-role-in-acute-pancreatitis,178183,0,2.html |
| _version_ | 1827287704130289664 |
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| author | Saira Rafaqat Dimitrios Patoulias Amir Hossein Behnoush Saima Sharif Aleksandra Klisic |
| author_facet | Saira Rafaqat Dimitrios Patoulias Amir Hossein Behnoush Saima Sharif Aleksandra Klisic |
| author_sort | Saira Rafaqat |
| collection | DOAJ |
| description | Acute pancreatitis (AP) is a common inflammatory state characterized by a clinical course that can lead to serious local and extrapancreatic organ malfunction and failure. Interleukins (ILs) are biologically active glycoproteins primarily produced by macrophages and lymphocytes. According to the literature, there are many ILs. However, this article represents a summary of the role of ILs in AP, such as IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-11, IL-12, IL-13, IL-14, IL-15, IL-16, IL-17, IL-18, IL-19, and IL-20. The ways to modulate IL activity to reduce inflammation and improve outcomes in individuals with this condition are under investigation. Drugs that target specific ILs might be developed to mitigate the effects of AP. |
| first_indexed | 2024-04-24T11:16:29Z |
| format | Article |
| id | doaj.art-cf3ceeb3fe7b4aedadd0258d798eddf6 |
| institution | Directory Open Access Journal |
| issn | 1734-1922 1896-9151 |
| language | English |
| last_indexed | 2024-04-24T11:16:29Z |
| publishDate | 2024-01-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Archives of Medical Science |
| spelling | doaj.art-cf3ceeb3fe7b4aedadd0258d798eddf62024-04-11T08:11:15ZengTermedia Publishing HouseArchives of Medical Science1734-19221896-91512024-01-0120113815610.5114/aoms/178183178183Interleukins: pathophysiological role in acute pancreatitisSaira Rafaqat0Dimitrios Patoulias1Amir Hossein Behnoush2Saima Sharif3Aleksandra Klisic4https://orcid.org/0000-0001-7870-0996Department of Zoology, Lahore College for Women University, Lahore, Punjab, PakistanOutpatient Department of Cardiometabolic Medicine, Second Department of Cardiology, Aristotle University of Thessaloniki, General Hospital "Hippokration", Thessaloniki, GreeceSchool of Medicine, Tehran University of Medical Sciences, Tehran, IranDepartment of Zoology, Lahore College for Women University, Lahore, Punjab, PakistanUniversity of Montenegro-Faculty of Medicine, Podgorica, MontenegroAcute pancreatitis (AP) is a common inflammatory state characterized by a clinical course that can lead to serious local and extrapancreatic organ malfunction and failure. Interleukins (ILs) are biologically active glycoproteins primarily produced by macrophages and lymphocytes. According to the literature, there are many ILs. However, this article represents a summary of the role of ILs in AP, such as IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-11, IL-12, IL-13, IL-14, IL-15, IL-16, IL-17, IL-18, IL-19, and IL-20. The ways to modulate IL activity to reduce inflammation and improve outcomes in individuals with this condition are under investigation. Drugs that target specific ILs might be developed to mitigate the effects of AP.https://www.archivesofmedicalscience.com/Interleukins-pathophysiological-role-in-acute-pancreatitis,178183,0,2.htmlinflammationinterleukinsacute pancreatitispathogenesis |
| spellingShingle | Saira Rafaqat Dimitrios Patoulias Amir Hossein Behnoush Saima Sharif Aleksandra Klisic Interleukins: pathophysiological role in acute pancreatitis Archives of Medical Science inflammation interleukins acute pancreatitis pathogenesis |
| title | Interleukins: pathophysiological role in acute pancreatitis |
| title_full | Interleukins: pathophysiological role in acute pancreatitis |
| title_fullStr | Interleukins: pathophysiological role in acute pancreatitis |
| title_full_unstemmed | Interleukins: pathophysiological role in acute pancreatitis |
| title_short | Interleukins: pathophysiological role in acute pancreatitis |
| title_sort | interleukins pathophysiological role in acute pancreatitis |
| topic | inflammation interleukins acute pancreatitis pathogenesis |
| url | https://www.archivesofmedicalscience.com/Interleukins-pathophysiological-role-in-acute-pancreatitis,178183,0,2.html |
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