State of the Art Biocompatible Gold Nanoparticles for Cancer Theragnosis
Research on cancer theragnosis with gold nanoparticles (AuNPs) has rapidly increased, as AuNPs have many useful characteristics for various biomedical applications, such as biocompatibility, tunable optical properties, enhanced permeability and retention (EPR), localized surface plasmon resonance (L...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-07-01
|
| Series: | Pharmaceutics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4923/12/8/701 |
| _version_ | 1797561400126603264 |
|---|---|
| author | Moon Sung Kang So Yun Lee Ki Su Kim Dong-Wook Han |
| author_facet | Moon Sung Kang So Yun Lee Ki Su Kim Dong-Wook Han |
| author_sort | Moon Sung Kang |
| collection | DOAJ |
| description | Research on cancer theragnosis with gold nanoparticles (AuNPs) has rapidly increased, as AuNPs have many useful characteristics for various biomedical applications, such as biocompatibility, tunable optical properties, enhanced permeability and retention (EPR), localized surface plasmon resonance (LSPR), photothermal properties, and surface enhanced Raman scattering (SERS). AuNPs have been widely utilized in cancer theragnosis, including phototherapy and photoimaging, owing to their enhanced solubility, stability, biofunctionality, cancer targetability, and biocompatibility. In this review, specific characteristics and recent modifications of AuNPs over the past decade are discussed, as well as their application in cancer theragnostics and future perspectives. In the future, AuNP-based cancer theragnosis is expected to facilitate the development of innovative and novel strategies for cancer therapy. |
| first_indexed | 2024-03-10T18:13:24Z |
| format | Article |
| id | doaj.art-cf3d035ca23941aa90781d41f400dd2d |
| institution | Directory Open Access Journal |
| issn | 1999-4923 |
| language | English |
| last_indexed | 2024-03-10T18:13:24Z |
| publishDate | 2020-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceutics |
| spelling | doaj.art-cf3d035ca23941aa90781d41f400dd2d2023-11-20T07:56:43ZengMDPI AGPharmaceutics1999-49232020-07-0112870110.3390/pharmaceutics12080701State of the Art Biocompatible Gold Nanoparticles for Cancer TheragnosisMoon Sung Kang0So Yun Lee1Ki Su Kim2Dong-Wook Han3Department of Cogno-Mechatronics Engineering, College of Nanoscience and Nanotechnology, Pusan National University, 2 Busandaehak-ro 63 beon-gil, Geumjeong-gu, Busan 46241, KoreaDepartment of Organic Materials Science and Engineering, College of Engineering, Pusan National University, 2 Busandaehak-ro 63 beon-gil, Geumjeong-gu, Busan 46241, KoreaDepartment of Organic Materials Science and Engineering, College of Engineering, Pusan National University, 2 Busandaehak-ro 63 beon-gil, Geumjeong-gu, Busan 46241, KoreaDepartment of Cogno-Mechatronics Engineering, College of Nanoscience and Nanotechnology, Pusan National University, 2 Busandaehak-ro 63 beon-gil, Geumjeong-gu, Busan 46241, KoreaResearch on cancer theragnosis with gold nanoparticles (AuNPs) has rapidly increased, as AuNPs have many useful characteristics for various biomedical applications, such as biocompatibility, tunable optical properties, enhanced permeability and retention (EPR), localized surface plasmon resonance (LSPR), photothermal properties, and surface enhanced Raman scattering (SERS). AuNPs have been widely utilized in cancer theragnosis, including phototherapy and photoimaging, owing to their enhanced solubility, stability, biofunctionality, cancer targetability, and biocompatibility. In this review, specific characteristics and recent modifications of AuNPs over the past decade are discussed, as well as their application in cancer theragnostics and future perspectives. In the future, AuNP-based cancer theragnosis is expected to facilitate the development of innovative and novel strategies for cancer therapy.https://www.mdpi.com/1999-4923/12/8/701gold nanoparticle (AuNP)cancer therapytheragnosisphotothermal treatment (PTT)photodynamic therapy (PDT)cancer imaging |
| spellingShingle | Moon Sung Kang So Yun Lee Ki Su Kim Dong-Wook Han State of the Art Biocompatible Gold Nanoparticles for Cancer Theragnosis Pharmaceutics gold nanoparticle (AuNP) cancer therapy theragnosis photothermal treatment (PTT) photodynamic therapy (PDT) cancer imaging |
| title | State of the Art Biocompatible Gold Nanoparticles for Cancer Theragnosis |
| title_full | State of the Art Biocompatible Gold Nanoparticles for Cancer Theragnosis |
| title_fullStr | State of the Art Biocompatible Gold Nanoparticles for Cancer Theragnosis |
| title_full_unstemmed | State of the Art Biocompatible Gold Nanoparticles for Cancer Theragnosis |
| title_short | State of the Art Biocompatible Gold Nanoparticles for Cancer Theragnosis |
| title_sort | state of the art biocompatible gold nanoparticles for cancer theragnosis |
| topic | gold nanoparticle (AuNP) cancer therapy theragnosis photothermal treatment (PTT) photodynamic therapy (PDT) cancer imaging |
| url | https://www.mdpi.com/1999-4923/12/8/701 |
| work_keys_str_mv | AT moonsungkang stateoftheartbiocompatiblegoldnanoparticlesforcancertheragnosis AT soyunlee stateoftheartbiocompatiblegoldnanoparticlesforcancertheragnosis AT kisukim stateoftheartbiocompatiblegoldnanoparticlesforcancertheragnosis AT dongwookhan stateoftheartbiocompatiblegoldnanoparticlesforcancertheragnosis |