Endoplasmic Reticulum Stress in Macrophages: The Vicious Circle of Lipid Accumulation and Pro-Inflammatory Response

Endoplasmic Reticulum Stress in Macrophages: The Vicious Circle of Lipid Accumulation and Pro-Inflammatory Response

The endoplasmic reticulum (ER) stress is an important event in the pathogenesis of different human disorders, including atherosclerosis. ER stress leads to disturbance of cellular homeostasis, apoptosis, and in the case of macrophages, to foam cell formation and pro-inflammatory cytokines production...

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Bibliographic Details
Main Authors: Vasily N. Sukhorukov, Victoria A. Khotina, Mariam Bagheri Ekta, Ekaterina A. Ivanova, Igor A. Sobenin, Alexander N. Orekhov
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Biomedicines
Subjects:
atherosclerosis
endoplasmic reticulum stress
macrophages
pro-inflammatory response
foam cells
Online Access:https://www.mdpi.com/2227-9059/8/7/210

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https://www.mdpi.com/2227-9059/8/7/210

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