Co-Delivery of Berberine Chloride and Tariquidar in Nanoliposomes Enhanced Intracellular Berberine Chloride in a Doxorubicin-Resistant K562 Cell Line Due to P-gp Overexpression

Co-Delivery of Berberine Chloride and Tariquidar in Nanoliposomes Enhanced Intracellular Berberine Chloride in a Doxorubicin-Resistant K562 Cell Line Due to P-gp Overexpression

The MDR phenomenon has become a major obstacle in the treatment of cancers, and among the strategies to reverse it, the inhibition of P-gp function and expression is essential to increase for effective anticancer drugs. In the present paper, the co-delivery of berberine chloride and tariquidar loade...

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Bibliographic Details
Main Authors: Giulia Vanti, Marcella Coronnello, Daniele Bani, Antonella Mannini, Maria Camilla Bergonzi, Anna Rita Bilia
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Pharmaceutics
Subjects:
MDR
berberine chloride
tariquidar
nanoliposomes
endocytosis
uptake
Online Access:https://www.mdpi.com/1999-4923/13/3/306

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