The Role of the Intestinal Microbiome in Multiple Sclerosis—Lessons to Be Learned from Hippocrates

Based on recent advances in research of chronic inflammatory conditions, there is a growing body of evidence that suggests a close correlation between the microbiota of the gastrointestinal tract and the physiologic activity of the immune system. This raises the idea that disturbances of the GI ecos...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Mohamed Mahmoud El-Sayed, Sidhesh Mohak, Dhir Gala, Reka Fabian, Zoltan Peterfi, Zsolt Fabian
التنسيق: مقال
اللغة:English
منشور في: MDPI AG 2023-11-01
سلاسل:Biology
الموضوعات:
الوصول للمادة أونلاين:https://www.mdpi.com/2079-7737/12/12/1463
الوصف
الملخص:Based on recent advances in research of chronic inflammatory conditions, there is a growing body of evidence that suggests a close correlation between the microbiota of the gastrointestinal tract and the physiologic activity of the immune system. This raises the idea that disturbances of the GI ecosystem contribute to the unfolding of chronic diseases including neurodegenerative pathologies. Here, we overview our current understanding on the putative interaction between the gut microbiota and the immune system from the aspect of multiple sclerosis, one of the autoimmune conditions accompanied by severe chronic neuroinflammation that affects millions of people worldwide.
تدمد:2079-7737