The association of aortic elasticity properties with novel inflammatory marker CRP /albumin ratio
Objective Hypertension (HT) is the most important preventable cause of cardiovascular disease and mortality. Aortic elasticity parameters are affected in HT, and inflammation plays a central role in the development of HT. C-reactive protein (CRP) to albumin ratio (CAR) is a novel inflammatory marker...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2021-11-01
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| Series: | Clinical and Experimental Hypertension |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/10641963.2021.1960368 |
| _version_ | 1797681120840515584 |
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| author | Mustafa Karanfil Kadriye Gayretli Yayla |
| author_facet | Mustafa Karanfil Kadriye Gayretli Yayla |
| author_sort | Mustafa Karanfil |
| collection | DOAJ |
| description | Objective Hypertension (HT) is the most important preventable cause of cardiovascular disease and mortality. Aortic elasticity parameters are affected in HT, and inflammation plays a central role in the development of HT. C-reactive protein (CRP) to albumin ratio (CAR) is a novel inflammatory marker. We aimed to evaluate the association of aortic elasticity properties with CAR. Methods A total of newly diagnosed untreated 101 hypertensive patients and 98 control participants were included to study. Clinical, demographic parameters, and blood sample parameters were recorded. Aortic strain, aortic stiffness index (ASI), and aortic distensibility (AoD) as aortic elasticity parameters were obtained from transthoracic echocardiography. Results CRP, CAR, ASI were significantly higher in hypertensive patients. (6.32 ± 2.48 vs 8.41 ± 3.35, p:<0.001; 0.158 ± 0.065 vs. 0.204 ± 0.083, p: <0.001; 6.73 ± 1.00 vs. 10.93 ± 1.81, p: <0.001, respectively) Aortic strain and AoD levels were significantly lower in hypertensive patients. (6.75 ± 2.17 vs 7.98 ± 2.27; p: <0.001 vs. 3.05 ± 0.97 vs 5.16 ± 1.01; p: <0.001, respectively) Conclusion CAR a novel inflammatory marker, which can be obtained from blood samples without additional time and cost, can be useful to predict aortic elasticity properties of hypertensive patients in daily clinical practice. |
| first_indexed | 2024-03-11T23:40:16Z |
| format | Article |
| id | doaj.art-cf41d188239d4d088a542156afe19b16 |
| institution | Directory Open Access Journal |
| issn | 1064-1963 1525-6006 |
| language | English |
| last_indexed | 2024-03-11T23:40:16Z |
| publishDate | 2021-11-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Clinical and Experimental Hypertension |
| spelling | doaj.art-cf41d188239d4d088a542156afe19b162023-09-19T16:04:07ZengTaylor & Francis GroupClinical and Experimental Hypertension1064-19631525-60062021-11-0143878078710.1080/10641963.2021.19603681960368The association of aortic elasticity properties with novel inflammatory marker CRP /albumin ratioMustafa Karanfil0Kadriye Gayretli Yayla1Ankara City HospitalDr. Abdurrahman Yurtaslan Ankara Oncology Research Ang Training HospitalObjective Hypertension (HT) is the most important preventable cause of cardiovascular disease and mortality. Aortic elasticity parameters are affected in HT, and inflammation plays a central role in the development of HT. C-reactive protein (CRP) to albumin ratio (CAR) is a novel inflammatory marker. We aimed to evaluate the association of aortic elasticity properties with CAR. Methods A total of newly diagnosed untreated 101 hypertensive patients and 98 control participants were included to study. Clinical, demographic parameters, and blood sample parameters were recorded. Aortic strain, aortic stiffness index (ASI), and aortic distensibility (AoD) as aortic elasticity parameters were obtained from transthoracic echocardiography. Results CRP, CAR, ASI were significantly higher in hypertensive patients. (6.32 ± 2.48 vs 8.41 ± 3.35, p:<0.001; 0.158 ± 0.065 vs. 0.204 ± 0.083, p: <0.001; 6.73 ± 1.00 vs. 10.93 ± 1.81, p: <0.001, respectively) Aortic strain and AoD levels were significantly lower in hypertensive patients. (6.75 ± 2.17 vs 7.98 ± 2.27; p: <0.001 vs. 3.05 ± 0.97 vs 5.16 ± 1.01; p: <0.001, respectively) Conclusion CAR a novel inflammatory marker, which can be obtained from blood samples without additional time and cost, can be useful to predict aortic elasticity properties of hypertensive patients in daily clinical practice.http://dx.doi.org/10.1080/10641963.2021.1960368albuminaortic elasticity parametersc-reactive proteinhypertensioninflammation |
| spellingShingle | Mustafa Karanfil Kadriye Gayretli Yayla The association of aortic elasticity properties with novel inflammatory marker CRP /albumin ratio Clinical and Experimental Hypertension albumin aortic elasticity parameters c-reactive protein hypertension inflammation |
| title | The association of aortic elasticity properties with novel inflammatory marker CRP /albumin ratio |
| title_full | The association of aortic elasticity properties with novel inflammatory marker CRP /albumin ratio |
| title_fullStr | The association of aortic elasticity properties with novel inflammatory marker CRP /albumin ratio |
| title_full_unstemmed | The association of aortic elasticity properties with novel inflammatory marker CRP /albumin ratio |
| title_short | The association of aortic elasticity properties with novel inflammatory marker CRP /albumin ratio |
| title_sort | association of aortic elasticity properties with novel inflammatory marker crp albumin ratio |
| topic | albumin aortic elasticity parameters c-reactive protein hypertension inflammation |
| url | http://dx.doi.org/10.1080/10641963.2021.1960368 |
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