Core/Double-Sheath Composite Fibers from Poly(ethylene oxide), Poly(L-lactide) and Beeswax by Single-Spinneret Electrospinning
The conventional approach for preparation of core-sheath fibers is coaxial electrospinning. Single-spinneret electrospinning of emulsions is a much less common method to obtain core-sheath fibers. Core-sheath structure may be generated by electrospinning of homogeneous blend solutions; however, repo...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-11-01
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| Series: | Polymers |
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| Online Access: | https://www.mdpi.com/2073-4360/14/22/5036 |
| _version_ | 1797464116850327552 |
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| author | Selin Kyuchyuk Dilyana Paneva Nevena Manolova Iliya Rashkov Daniela Karashanova Nadya Markova |
| author_facet | Selin Kyuchyuk Dilyana Paneva Nevena Manolova Iliya Rashkov Daniela Karashanova Nadya Markova |
| author_sort | Selin Kyuchyuk |
| collection | DOAJ |
| description | The conventional approach for preparation of core-sheath fibers is coaxial electrospinning. Single-spinneret electrospinning of emulsions is a much less common method to obtain core-sheath fibers. Core-sheath structure may be generated by electrospinning of homogeneous blend solutions; however, reports on such cases are still scarce. Herein, the preparation of nanofibrous composites from poly(ethylene oxide) (PEO), poly(L-lactide) (PLA) and beeswax (BW) by single-spinneret electrospinning of their homogeneous blend solutions in chloroform is reported. The produced fibers had core/double-sheath structure with a PEO core, PLA inner sheath and BW outer sheath. This original fiber structure was evidenced by transmission electron microscopy, selective extraction of BW or PEO, and X-ray photoelectron spectroscopy. The PLA/BW double sheath led to hydrophobicity of the PEO/PLA/BW mats. The tensile tests revealed that PEO/PLA/BW mats had substantially improved mechanical behavior as compared to PEO, PLA and PEO/BW mats. PEO/PLA/BW mats can be used as drug carriers as evidenced by the one-pot incorporation of the model drug 5-nitro-8-hydroxyquinoline (NQ) into the fibrous materials. Microbiological tests showed that PEO/PLA/BW/NQ had antimicrobial activity. Therefore, the new materials are promising for wound healing applications. |
| first_indexed | 2024-03-09T18:03:22Z |
| format | Article |
| id | doaj.art-cf4253dd5ad8445c9290cb6325282457 |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-03-09T18:03:22Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-cf4253dd5ad8445c9290cb63252824572023-11-24T09:45:11ZengMDPI AGPolymers2073-43602022-11-011422503610.3390/polym14225036Core/Double-Sheath Composite Fibers from Poly(ethylene oxide), Poly(L-lactide) and Beeswax by Single-Spinneret ElectrospinningSelin Kyuchyuk0Dilyana Paneva1Nevena Manolova2Iliya Rashkov3Daniela Karashanova4Nadya Markova5Laboratory of Bioactive Polymers, Institute of Polymers, Bulgarian Academy of Sciences, Acad. G. Bonchev St., Bl. 103A, BG-1113 Sofia, BulgariaLaboratory of Bioactive Polymers, Institute of Polymers, Bulgarian Academy of Sciences, Acad. G. Bonchev St., Bl. 103A, BG-1113 Sofia, BulgariaLaboratory of Bioactive Polymers, Institute of Polymers, Bulgarian Academy of Sciences, Acad. G. Bonchev St., Bl. 103A, BG-1113 Sofia, BulgariaLaboratory of Bioactive Polymers, Institute of Polymers, Bulgarian Academy of Sciences, Acad. G. Bonchev St., Bl. 103A, BG-1113 Sofia, BulgariaInstitute of Optical Materials and Technologies, Bulgarian Academy of Sciences, Akad. G. Bonchev St., Bl. 109, BG-1113 Sofia, BulgariaInstitute of Microbiology, Bulgarian Academy of Sciences, Akad. G. Bonchev St., Bl. 26, BG-1113 Sofia, BulgariaThe conventional approach for preparation of core-sheath fibers is coaxial electrospinning. Single-spinneret electrospinning of emulsions is a much less common method to obtain core-sheath fibers. Core-sheath structure may be generated by electrospinning of homogeneous blend solutions; however, reports on such cases are still scarce. Herein, the preparation of nanofibrous composites from poly(ethylene oxide) (PEO), poly(L-lactide) (PLA) and beeswax (BW) by single-spinneret electrospinning of their homogeneous blend solutions in chloroform is reported. The produced fibers had core/double-sheath structure with a PEO core, PLA inner sheath and BW outer sheath. This original fiber structure was evidenced by transmission electron microscopy, selective extraction of BW or PEO, and X-ray photoelectron spectroscopy. The PLA/BW double sheath led to hydrophobicity of the PEO/PLA/BW mats. The tensile tests revealed that PEO/PLA/BW mats had substantially improved mechanical behavior as compared to PEO, PLA and PEO/BW mats. PEO/PLA/BW mats can be used as drug carriers as evidenced by the one-pot incorporation of the model drug 5-nitro-8-hydroxyquinoline (NQ) into the fibrous materials. Microbiological tests showed that PEO/PLA/BW/NQ had antimicrobial activity. Therefore, the new materials are promising for wound healing applications.https://www.mdpi.com/2073-4360/14/22/5036electrospinningnanofibrous compositecore/double-sheath fiberscore-shell fibersbeeswaxpoly(L-lactide) |
| spellingShingle | Selin Kyuchyuk Dilyana Paneva Nevena Manolova Iliya Rashkov Daniela Karashanova Nadya Markova Core/Double-Sheath Composite Fibers from Poly(ethylene oxide), Poly(L-lactide) and Beeswax by Single-Spinneret Electrospinning Polymers electrospinning nanofibrous composite core/double-sheath fibers core-shell fibers beeswax poly(L-lactide) |
| title | Core/Double-Sheath Composite Fibers from Poly(ethylene oxide), Poly(L-lactide) and Beeswax by Single-Spinneret Electrospinning |
| title_full | Core/Double-Sheath Composite Fibers from Poly(ethylene oxide), Poly(L-lactide) and Beeswax by Single-Spinneret Electrospinning |
| title_fullStr | Core/Double-Sheath Composite Fibers from Poly(ethylene oxide), Poly(L-lactide) and Beeswax by Single-Spinneret Electrospinning |
| title_full_unstemmed | Core/Double-Sheath Composite Fibers from Poly(ethylene oxide), Poly(L-lactide) and Beeswax by Single-Spinneret Electrospinning |
| title_short | Core/Double-Sheath Composite Fibers from Poly(ethylene oxide), Poly(L-lactide) and Beeswax by Single-Spinneret Electrospinning |
| title_sort | core double sheath composite fibers from poly ethylene oxide poly l lactide and beeswax by single spinneret electrospinning |
| topic | electrospinning nanofibrous composite core/double-sheath fibers core-shell fibers beeswax poly(L-lactide) |
| url | https://www.mdpi.com/2073-4360/14/22/5036 |
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