3D Collagen Fiber Concentration Regulates Treg Cell Infiltration in Triple Negative Breast Cancer

3D Collagen Fiber Concentration Regulates Treg Cell Infiltration in Triple Negative Breast Cancer

BackgroundTriple negative breast cancer (TNBC) is characterized by poor prognosis and a lack of effective therapeutic agents owing to the absence of biomarkers. A high abundance of tumor-infiltrating regulatory T cells (Tregs) was associated with worse prognosis in malignant disease. Exploring the a...

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Bibliographic Details
Main Authors: Huan Gao, Qi Tian, Yan Zhou, Lizhe Zhu, Yinliang Lu, Yingying Ma, Jinteng Feng, Yina Jiang, Bo Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
triple negative breast cancer
tumor microenvironment
regulatory T cells
extracellular matrix
tumor-infiltrating lymphocytes
prognostic model
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.904418/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.904418/full

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