Detection of Antimalarial Resistance-Associated Mutations in Plasmodium falciparum via a Platform of Allele-Specific PCR Combined with a Gold Nanoparticle-Based Lateral Flow Assay

Detection of Antimalarial Resistance-Associated Mutations in Plasmodium falciparum via a Platform of Allele-Specific PCR Combined with a Gold Nanoparticle-Based Lateral Flow Assay

ABSTRACT Since single nucleotide polymorphisms (SNPs) have attracted attention, there have been many explorations and improvements in screening and detection methods for SNPs. Traditional methods are complex and time-consuming and rely on expensive instruments. Therefore, there is an urgent need for...

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Bibliographic Details
Main Authors: Weijia Cheng, Wei Wang, Huiyin Zhu, Xiaonan Song, Kai Wu, Jian Li
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:Microbiology Spectrum
Subjects:
malaria
mutation
Pfmdr1
Plasmodium falciparum
antimalarial drug resistance
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02535-22

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