Fyn-Mediated Paxillin Tyrosine 31 Phosphorylation Regulates Migration and Invasion of Breast Cancer Cells
Metastasis is the leading cause of death in breast cancer patients due to the lack of effective therapies. Elevated levels of paxillin expression have been observed in various cancer types, with tyrosine phosphorylation shown to play a critical role in driving cancer cell migration. However, the spe...
Main Authors: | Ying Zhang, Huanyu Zheng, Ming Xu, Noriko Maeda, Ryouichi Tsunedomi, Hiroko Kishi, Hiroaki Nagano, Sei Kobayashi |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-11-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/24/21/15980 |
Similar Items
-
Paxillin participates in the sphingosylphosphorylcholine-induced abnormal contraction of vascular smooth muscle by regulating Rho-kinase activation
by: Ying Zhang, et al.
Published: (2024-01-01) -
Fyn Tyrosine Kinase Elicits Amyloid Precursor Protein Tyr682 Phosphorylation in Neurons from Alzheimer’s Disease Patients
by: Filomena Iannuzzi, et al.
Published: (2020-07-01) -
FYN/TOPK/HSPB1 axis facilitates the proliferation and metastasis of gastric cancer
by: SanFei Peng, et al.
Published: (2023-04-01) -
Development and Evaluation of Monoclonal Antibodies for Paxilline
by: Chris M. Maragos
Published: (2015-09-01) -
Fyn Tyrosine Kinase as Harmonizing Factor in Neuronal Functions and Dysfunctions
by: Carmela Matrone, et al.
Published: (2020-06-01)