Intrauterine inflammation, infection, or both (Triple I): A new concept for chorioamnionitis

Chorioamnionitis is a common cause of preterm birth and may cause adverse neonatal outcomes, including neurodevelopmental sequelae. Chorioamnionitis has been marked to a heterogeneous setting of conditions characterized by infection or inflammation or both, followed by a great variety in clinical pr...

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Main Authors: Chun-Chih Peng, Jui-Hsing Chang, Hsiang-Yu Lin, Po-Jen Cheng, Bai-Horng Su
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Pediatrics and Neonatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S187595721730027X
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author Chun-Chih Peng
Jui-Hsing Chang
Hsiang-Yu Lin
Po-Jen Cheng
Bai-Horng Su
author_facet Chun-Chih Peng
Jui-Hsing Chang
Hsiang-Yu Lin
Po-Jen Cheng
Bai-Horng Su
author_sort Chun-Chih Peng
collection DOAJ
description Chorioamnionitis is a common cause of preterm birth and may cause adverse neonatal outcomes, including neurodevelopmental sequelae. Chorioamnionitis has been marked to a heterogeneous setting of conditions characterized by infection or inflammation or both, followed by a great variety in clinical practice for mothers and their newborns. Recently, a descriptive term: “intrauterine inflammation or infection or both” abbreviated as “Triple I” has been proposed by a National Institute of Child Health and Human Development expert panel to replace the term chorioamnionitis. It is particularly important to recognize that an isolated maternal fever does not automatically equate to chorioamnionitis. This article will review the current literature on chorioamnionitis, and introduce the concept of Triple I, as well as recommendations for assessment and management of pregnant women and their newborns with a diagnosis of Triple I.
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spelling doaj.art-cf496ebed1b6473c8b15c109b68ad7c82022-12-21T20:07:48ZengElsevierPediatrics and Neonatology1875-95722018-06-0159323123710.1016/j.pedneo.2017.09.001Intrauterine inflammation, infection, or both (Triple I): A new concept for chorioamnionitisChun-Chih Peng0Jui-Hsing Chang1Hsiang-Yu Lin2Po-Jen Cheng3Bai-Horng Su4Department of Medicine, Mackay Medical College, Taipei, TaiwanDepartment of Medicine, Mackay Medical College, Taipei, TaiwanDepartment of Neonatology, China Medical University Children's Hospital, Taichung, TaiwanDepartment of Obstetrics, Chang Gung Memorial Hospital, Taoyuan, TaiwanDepartment of Neonatology, China Medical University Children's Hospital, Taichung, TaiwanChorioamnionitis is a common cause of preterm birth and may cause adverse neonatal outcomes, including neurodevelopmental sequelae. Chorioamnionitis has been marked to a heterogeneous setting of conditions characterized by infection or inflammation or both, followed by a great variety in clinical practice for mothers and their newborns. Recently, a descriptive term: “intrauterine inflammation or infection or both” abbreviated as “Triple I” has been proposed by a National Institute of Child Health and Human Development expert panel to replace the term chorioamnionitis. It is particularly important to recognize that an isolated maternal fever does not automatically equate to chorioamnionitis. This article will review the current literature on chorioamnionitis, and introduce the concept of Triple I, as well as recommendations for assessment and management of pregnant women and their newborns with a diagnosis of Triple I.http://www.sciencedirect.com/science/article/pii/S187595721730027Xchorioamnionitisintrauterine inflammation or infectionTriple I
spellingShingle Chun-Chih Peng
Jui-Hsing Chang
Hsiang-Yu Lin
Po-Jen Cheng
Bai-Horng Su
Intrauterine inflammation, infection, or both (Triple I): A new concept for chorioamnionitis
Pediatrics and Neonatology
chorioamnionitis
intrauterine inflammation or infection
Triple I
title Intrauterine inflammation, infection, or both (Triple I): A new concept for chorioamnionitis
title_full Intrauterine inflammation, infection, or both (Triple I): A new concept for chorioamnionitis
title_fullStr Intrauterine inflammation, infection, or both (Triple I): A new concept for chorioamnionitis
title_full_unstemmed Intrauterine inflammation, infection, or both (Triple I): A new concept for chorioamnionitis
title_short Intrauterine inflammation, infection, or both (Triple I): A new concept for chorioamnionitis
title_sort intrauterine inflammation infection or both triple i a new concept for chorioamnionitis
topic chorioamnionitis
intrauterine inflammation or infection
Triple I
url http://www.sciencedirect.com/science/article/pii/S187595721730027X
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