Evaluation of Load-To-Strength Ratios in Metastatic Vertebrae and Comparison With Age- and Sex-Matched Healthy Individuals

Evaluation of Load-To-Strength Ratios in Metastatic Vertebrae and Comparison With Age- and Sex-Matched Healthy Individuals

Vertebrae containing osteolytic and osteosclerotic bone metastases undergo pathologic vertebral fracture (PVF) when the lesioned vertebrae fail to carry daily loads. We hypothesize that task-specific spinal loading patterns amplify the risk of PVF, with a higher degree of risk in osteolytic than in...

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Bibliographic Details
Main Authors:	Dennis E. Anderson, Michael W. Groff, Thomas F. Flood, Brett T. Allaire, Roger B. Davis, Marc A. Stadelmann, Philippe K. Zysset, Ron N. Alkalay
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-08-01
Series:	Frontiers in Bioengineering and Biotechnology
Subjects:	spine metastatic disease musculoskeletal models vertebral strength load-to-strength ratio
Online Access:	https://www.frontiersin.org/articles/10.3389/fbioe.2022.866970/full

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